National Cancer Institute, Research Contracts Branch, PSAS, 6120 Executive Blvd, EPS/Room 638, Bethesda, MD 20892-7227

66 -- VISUALSONICS VS40 ULTRASOUND IMAGING SYSTEMS FOR MICE SOL NCI-RFQ-00129-NV DUE 061200 POC Debbie Moore, Purchasing Agent (301) 402-4509, Todd Cole, Contracting Officer (301) 402-4509 The National Institutes of Health, National Cancer Institute (NCI), on behalf of the National Institute of Neurological Disorders and Stroke (NINDS), plans to procure a VS40 ultrasound imaging system for use on mice from VisualSonics, through Sunnybrook and Women s College Health Science Center, 2075 Bayview Ave., Toronto, Ontario, Canada M4N3N5. NINDS requires a commercially available ultrasound imaging system in order to further develop the use of imaging modalities to non-invasively phenotype and study genetically modified animals. The specific objective of this project is to secure an ultrasound capable of reaching a transducer resonance frequency able to study transgenic mouse models. Towards these goals, the contractor needs to provide a high resolution ultrasound capable of obtaining 40mHz or greater (not to exceed 50 MHz) to image structural anatomy of embryonic mouse tissue or in utero imaging of mouse embryos. The design and performance of this ultrasound should be state of the art in that it has an ability for imaging technic and data processing. The VS40 ultrasound imaging system from VisualSonics is the only system known by the NINDS researcher that can produce a minimum transducer frequency of 40mHz or more. This is the minimum frequency needed to resolve anatomical structures in the mouse embryo from gestation day 8 to day 9. In addition, the system is unique in that it provides: 1)2D, M-mode, pulsed doppler, and CW doppler scanning and 2) DICOM conformance of the acquired images for acqusition and transmission in DICOM. VisualSonics is the only organization known to the NINDS researcher that has aforementioned features that are required and believed to be unique. This is not a request for competitive quotation. However, if any interested party believes it can meet the above requirement and the noted features, it may submit a statement of capabilities. The statement of capabilities and any other information furnished must be in writing and must contain material in sufficient detail to allow NCI/NINDS to determine if the party can perform this requirement. An original and one copy of the capability statements must bereceived in the contracting office by 2:00 PM EDT, on June 12, 2000. If you have any questions, please contact Debbie Moore, Purchasing Agent on (301) 402-4509. A determination by the Government not to compete this proposed requirement based upon responses to this notice is solely within the discretion of the Government. Information received will be considered solely for the purpose of determining whether to conduct a competitive procurement. Posted 05/24/00 (W-SN458211). (0145)

Loren Data Corp. http://www.ld.com (SYN# 0431 20000526\66-0016.SOL)