REQUEST FOR INFORMATION ON "HMG CO-A REDUCTASE INHIBITOR" PRODUCT GROUP(S), COMMONLY KNOWN AS "STATINS" The Defense Supply Center Philadelphia (DSCP) intends to issue solicitation #SPO200-98-R-2503 for "HMG-CoA Reductase Inhibitor" products group(s), commonly known as "Statins". The product group must be FDA approved as of the issuance date of the solicitation. At the time of issuance of this notice, DSCP is aware of only the following statins, which meet the preceding requirement, atorvastatin, cerivastatin, fluvastatin, lovastatin, pravastatin and simvastatin. -- -- -- -- -- -- Prior to issuance of the solicitation, pharmaceutical companies are hereby invited, but not required, to make a presentation about the clinical attributes of their statins at the DoD Pharmacoeconomic Center, Fort Sam Houston, Texas between 18 August 1998 and 14 September 1998. One presentation will be permitted for each statin. Each presentation will be limited to no more than one hour. Companies may schedule their presentations by contacting MAJ Donald DeGroff at the DoD Pharmacoeconomic Center, telephone 210-295-9635 or 210-295-1271. Pharmaceutical companies are encouraged to provide the following information concerning their statins: (1) Point estimates of the average percentage reduction in low-density lipoprotein cholesterol (LDL-C) that would be achieved at each dosage for the statin and identification of the studies on which the point estimates are based. (2) Studies showing the effect that the statin has on the incidence of fatal and nonfatal myocardial infarctions. (3) A comparison of the statin to other statins regarding safety issues such as the incidence of adverse effects and the incidence of clinically significant drug interactions. (4) Any other information pertaining to clinically significant differences between the statin and other statins. NOTE: The Government may use information provided during the presentations when drafting its solicitation. However, all awards will be based on the offers received in response to the actual solicitation and the evaluation criteria set forth therein. E-MAIL: Click here to contact the contracting officer via, wdilauro@dscp.dla.mil. Posted 08/17/98 (W-SN237822).

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