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COMMERCE BUSINESS DAILY ISSUE OF AUGUST 11,1998 PSA#2156National Cancer Institute, Research Contracts Branch, PSAS, 6120
Executive Blvd, EPS/Room 638, Bethesda, MD 20892-7227 67 -- VARIO -- SPEED SLOW SCAN CAMERA SYSTEM SOL RFQ80189-NS DUE
082498 POC Patricia Haun, 301-496-8613 The National Cancer Institute
(NCI), on behalf of National Institute of Neurological Disorder and
Stroke (NINDS), Laboratory of Neurobiology (LN), plans to procure a
low-noise, scienitfic-grade, charge-coupled device (CCD) camera
(Vario-Speed Slow Scan Camera System) from Leo Electron Microscopy
Inc., 1 Zeiss Drive, Thornwood, NY 10594. The Laboratory of
Neurobiology (LN) is responsible for investigating the fundamental cell
biology of synaptic transmission, intracellular transport and the
organization of specialized membranes in neurons. Important components
of these studies concern calcium regulation of neuronal processes and
the molecular organization of intracellular assemblies. Many of the
principle techniques of modern structural biology, especially advanced
electron microscopy and low-temperature preservation techniques, are
essential tools in the Laboratory's research program. The LN's current
instrument for this research is a LEO 912 Omega energy-filtering
electron microscope, whose capabilities for low-dose, quantitative
imaging, energy filtering, and cryoelectron microscopy would be greatly
expanded by a sensitive CCD camera system. The CCD camera will be
installed on and interfaced to the Leo 912 Omega energy-filtering
electron microscope. The combination of these instruments will expand
the capability and improve the convenience of recording data from
rapidly frozen neuronal specimens, leading to an increase in research
productivity. A slow-scan CCD camera system is required, and it shall
be compatible to, installed on, and interfaced to the existing LEO 912
Omega energy-filtering electron microscope. The system shall include
the following: 1) a Proscan Vario-Speed camera with 1Kx1K chip or
equal; 2) independent, three stage peltier cooling and fiber-optic
coupling for stable temperature and noise control; 3) digital
controller with speeds of 2 Mhz at 14 bits and 5 Mhz at 8 bits; 4)
microscope mounting flange and hardware (yielding minimal undesirable
post-specimen magnification); 5)cooling device; 6) Windows/PC-based
custom control software with compatible processing routines for the
existing LEO 912 Omega electron microscope; 7) on-site installation and
set up to meet the required performance; and 8) a one-year on-site
parts and labor warranty. In addition, the camera system shall be
optimized for low-dose imaging of beam sensitive biological specimens
to provide a sensitivity of > 8 counts per incident electron.
Furthermore, the noise level under low-illumination conditions shall be
only one electron per readout or better. Leo Electron Microscopy, Inc.,
is the only source known to NINDS that can meet the above requirements
and provide a camera system that is fully compatible with the
mechanical, hardware, and software environment of the existing LEO 912
Omega electron microscope. However, if any interested party believes
it can meet the above specifications, it may submit a statement of
capabilities. The statement of capabilities and any other information
furnished must be in writing andmust contain material in sufficient
detail to allow NCI/NINDS to determine if the party can perform the
requirement. Capability Statements must be received in the contracting
office by 3:00 p.m. EST, on August 24, 1998. If you have any
questions, please contact Patricia Haun on (301) 402-4509. A
determination by the Government not to compete this proposed contract
based upon responses to this notice is solely within the discretion of
the Government. Information received will be considered solely for the
purpose of determining whether to conduct a competitive procurement.
Posted 08/07/98 (W-SN234333). (0219) Loren Data Corp. http://www.ld.com (SYN# 0372 19980811\67-0002.SOL)
67 - Photographic Equipment Index Page
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