DHHS/National Institute on Alcohol Abuse and Alcoholism, Contracts Management Branch, Willco Building, Suite 504, 6000 Executive Boulevard, MSC 7003, Bethesda, Maryland 20892-7003

A -- AN AMERICAN INDIAN TRIBE WITH LOW ALCOHOLISM PREVALENCE: TRANSMISSION ANALYSIS, LINKAGE ANALYSIS AND GENE/ENVIRONMENT INTERACTIONS Sol. AA-96-03. Due 080996. POC: C. Timothy Crilley, Contract Specialist, Roberta S. Wilhelm, Contracting Officer, 301-443-1191. The National Institute on Alcohol Abuse and Alcoholism intends to negotiate on a sole-source basis with the Center for Human Behavior Studies, Incorporated for a research and development project entitled, ``An American Indian Tribe with Low Alcoholism Prevalence: Transmission Analysis, Linkage Analysis and Gene/Environment Interactions.'' The statutory authority to negotiate with the Center for Human Behavior Studies, Incorporated is 41 U.S.C.253(c)(1) under FAR reference 6.302-1. The purpose of the proposed contract is to rigorously define the prevalance of alcoholism and associated problems in an American Indian tribe with a purported low rate of alcoholism and alcohol abuse. Individual psychiatric interviews, groups sociocultural data, and blood samples will be collected to address issues of gene/environment interactions for alchoholism in the Choctaw American Indian Tribe. Additional individual information will be collected on severe trauma and stress, alcohol availability, and socioeconomic factors to identify how these variables interact in the development of alcoholism and related problems. The offerors must demonstrate an understanding of the implications of working with an American Indian population in tribal and personal interactions, methods employed to gather data from American Indian tribes, and how standard data collection instruments must be modified to be useful in this culture, and an ability to conduct rigorous scientific data collections under field conditions. Staff must be made in writing, telephone inquiries are unacceptable. See Note Numbers 22 and 26. (149)

Loren Data Corp. http://www.ld.com (SYN# 0005 19960604\A-0005.SOL)