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SAMDAILY.US - ISSUE OF MAY 01, 2025 SAM #8557
SOLICITATION NOTICE

66 -- Biorelevant characterization system for subcutaneous injections

Notice Date
4/29/2025 5:50:59 AM
 
Notice Type
Combined Synopsis/Solicitation
 
NAICS
334516 — Analytical Laboratory Instrument Manufacturing
 
Contracting Office
FDA OFFICE OF ACQ GRANT SVCS Beltsville MD 20705 USA
 
ZIP Code
20705
 
Solicitation Number
75F401F25R00066
 
Response Due
5/9/2025 9:00:00 AM
 
Archive Date
05/24/2025
 
Point of Contact
Erika Crawford, Phone: 3017960298
 
E-Mail Address
erika.crawford@fda.hhs.gov
(erika.crawford@fda.hhs.gov)
 
Small Business Set-Aside
SBA Total Small Business Set-Aside (FAR 19.5)
 
Description
The scope is to purchase and install an in vitro biorelevant characterization system for subcutaneous injections at the injection site in an artificial extracellular matrix (ECM) with integrated camera and turbidity sensors, inline fiber optic probes, pH monitors, and an automated sample fraction collector for unattended operation and media refill after sampling. The aim is to expand and augment the capacity and capability of CDER/OPQ/OPQR to ensure quality, safety and efficacy of pharmaceutical products. In particular, this in vitro system will offer the capability for investigating the release performance of subcutaneous formulations under simulated physiological conditions. It assesses the critical drug attributes, risk and performance of subcutaneously administered drugs including biologics, peptides and small molecules.
 
Web Link
SAM.gov Permalink
(https://sam.gov/opp/79f0c6d6d37d4d8c94041c4399534554/view)
 
Place of Performance
Address: Saint Louis, MO 63110, USA
Zip Code: 63110
Country: USA
 
Record
SN07425254-F 20250501/250429230056 (samdaily.us)
 
Source
SAM.gov Link to This Notice
(may not be valid after Archive Date)

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