SOLICITATION NOTICE
B -- Optimization of FT-EPR imaging methods
- Notice Date
- 6/1/2016
- Notice Type
- Presolicitation
- NAICS
- 541690
— Other Scientific and Technical Consulting Services
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Cancer Institute, Bldg 1050, Frederick, Maryland, 21702, United States
- ZIP Code
- 21702
- Solicitation Number
- N02RC62594-57
- Point of Contact
- Reyes Rodriguez, Phone: 240-276-5442
- E-Mail Address
-
reyes.rodriguez@nih.gov
(reyes.rodriguez@nih.gov)
- Small Business Set-Aside
- N/A
- Description
- Contracting Office Address Department of Health and Human Services, National Institutes of Health, National Cancer Institute, Office of Acquisitions, 9609 Medical Center Drive, Room 1E128, Bethesda, MD 20892, UNITED STATES. Description The National Cancer Institute (NCI), Biophysical Spectroscopy Section of the Radiation Biology Branch (RBB), CCR, plans to procure on a sole source basis consulting services and assistance to obtain analytical tools on general architecture of algorithms from GenEpria Consulting Inc, 10015 Old Columbia Rd, Suite B-215 Columbia, MD 21046. This acquisition will be processed under FAR Part 12 - Acquisition for Commercial Items and will be made pursuant to the authority in FAR 13.106-1 (b)(2) and 13.501-(a)(1) using simplified acquisition procedures for commercial acquisitions. The North American Industry Classification System code is 541690 and the business size standard is $14.0 Million. Only one award will be made as a result of this solicitation. This will be awarded as a firm fixed price type contract. The period of performance is twelve (12) months from date of award. It has been determined there are no opportunities to acquire green products or services for this procurement. The NCI and the RBB is conducting two major projects requiring both intensive statistical and programming applications. The first project involves studies on the effect of the antioxidant nitroxide, Tempol, on the gut microflora of mice continuously feed tempol containing mouse chow over many months. The second is a continuation project on radiation metabolomics to determine the metabolites predictive of cancer types. The RBB is preparing to set up another long term mouse urine metabolite study to see if short term metabolic profiles are predictive of cancer induction post IR (ionizing radiation) exposure. Contractor Requirements are: 1. Integrated EPR Oximetry suite for EPRI at 400 MHz frequency. The data acquisition and image reconstruction software for the EPRI system operating at 400 MHz providing an efficient work flow. The acquisition and display software is to be upgraded to the operating system of the computer running 400 MHz scanner. 2. Implementation of novel pulse programs for EPRI using waveform generator. Develop software to program the waveform generator for multi sequence pulse programs such as Hadamard, Frank and other pulse sequences that would reduce the specific absorption rate (SAR). Develop algorithm to pipeline the multi sequence acquisition data through the image reconstruction modules for EPRI at 400 MHz. 3. Real time visualization of FT-EPR imaging at 400 MHz. Develop algorithms for image visualization during acquisition. Devise faster image processing algorithms to allow the display of the image real time during acquisition. 4. Algorithms for Co-registration of images scanned by 400 MHz EPRI with other modalities. The purpose of this algorithm is to relate the quantities determined by MRI to the quantities determined by EPRI at 400 MHz such as pO2 in order to examine their relationships. 5. Oximetry by T2* mapping using single SPI-EPRI acquisition at 400 MHz. This requirement is to implement a new algorithm developed by RBB and University of Wisconsin to increase the speed of oxygen mapping by about 3 times in single point imaging (SPI) mode at 400 MHz. Oximetry by T2* conventionally requires three SPI-EPRI scans at three different maximum gradients. The new algorithm uses gridding and k-space extrapolation of data from single SPI-EPRI acquisition offering a three-fold scan speed and better image quality. 6. Statistical analysis of gut microbiota 16S sequencing data of mice on Tempol feed. Analyze the effect of the antioxidant nitroxide, Tempol, on the gut microflora of mice continuously feed tempol containing mouse chow over many months. Identify the specific signatures relevant to the tempol effect GenEpria has successfully completed previous assignments with RBB on similar approaches in this field. GenEpria previously developed custom made algorithms for co-registration among MRI, EPRI and other modalities for the use with oximetry from EPRI and anatomic and functional images obtained from MRI at 7T. Bringing another vendor at this point will force the Government to invest additional time and money to allow the new vendor to familiarized with existing algorithms. GenEpria is the only vendor known to perform the proposed Statement of Work by RBB. This notice is not a request for competitive quotation. However, if any interested party, especially small business believes it can meet the above requirement, it may submit a proposal or quote for the Government to consider. The response and any other information furnished must be in writing and must contain material in sufficient detail to allow NCI to determine if the party can perform the requirement. Responses must be received in the contracting office by 4 PM EST, on June 10, 2016. All responses and questions must be in writing and faxed to 240-276-5399 or emailed to Reyes Rodriguez, Contracting Officer via electronic mail at reyes.rodriguez@nih.gov. A determination by the Government not to compete this proposed requirement based upon responses to this notice is solely within the discretion of the Government. Information received will be considered solely for the purpose of determining whether to conduct a competitive procurement. No collect calls will be accepted. In order to receive an award, contractors must be registered and have valid certification in the Central Contractor Registration (CCR) and the Online Representations and Certifications Applications (ORCA) through sam.gov. Reference: N02RC62594-57 on all correspondence.
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/NIH/FCRF/N02RC62594-57/listing.html)
- Place of Performance
- Address: TBA, Bethesda, Maryland, 20892, United States
- Zip Code: 20892
- Zip Code: 20892
- Record
- SN04134176-W 20160603/160601234436-f362ac893ac1f9785eebdaf5fde9a6c9 (fbodaily.com)
- Source
-
FedBizOpps Link to This Notice
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