SOURCES SOUGHT
66 -- HiSeq 2500 (Brand Name: Illumina)
- Notice Date
- 2/4/2013
- Notice Type
- Sources Sought
- NAICS
- 334516
— Analytical Laboratory Instrument Manufacturing
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Heart, Lung and Blood Institute, Rockledge Dr. Bethesda, MD, Office of Acquisitions, 6701 Rockledge Dr RKL2/6100 MSC 7902, Bethesda, Maryland, 20892-7902
- ZIP Code
- 20892-7902
- Solicitation Number
- HHS-NIH-NHLBI-CSB-(HG)-2013-084-DLM
- Archive Date
- 3/2/2013
- Point of Contact
- Dorothy Maxwell, Phone: 301-435-0352
- E-Mail Address
-
maxwelld@mail.nih.gov
(maxwelld@mail.nih.gov)
- Small Business Set-Aside
- N/A
- Description
- This Sources Sought Notice (SS) is for information and planning purposes only and shall not be construed as a solicitation or as an obligation on the part of the National Heart, Lung, and Blood Institute (NHLBI). The purpose of this SS is to identify qualified small business concerns [including Small Disadvantaged Businesses (SDB), Woman-owned Small Businesses (WOSB), Historically Underutilized Business Zone (HUBZone) Small Businesses, Veteran-Owned Small Businesses (VOSB) and Service-Disabled Veteran-owned Small Businesses (SDVOSB] that are interested in and capable of providing: HiSeq 2500, (Specified Brand Name: Illumina) NO REFURBISHED OR USED SYSTEMS ARE ACCEPTABLE. The NHLBI does not intend to award a contract on the basis of responses nor otherwise pay for the preparation of any information submitted. As a result of this Sources Sought notice, the NHLBI may issue a Request for Quote (RFQ). THERE IS NO SOLICITATION AVAILABLE AT THIS TIME. However, should such a requirement materialize, no basis for claims against NHLBI shall arise as a result of a response to this Sources Sought notice or the NHLBI's use of such information as either part of our evaluation process or in developing specifications for any subsequent requirement. The NHLBI is seeking capability statements from all eligible small business concerns [particularly Small Disadvantaged Businesses (SDB), Woman-owned Small Businesses (WOSB), Historically Underutilized Business Zone (HUBZone) Small Businesses, Veteran-Owned Small Businesses (VOSB) and Service-Disabled Veteran-owned Small Businesses (SDVOSB)] under the North American Industry Classification System (NAICS) code 334516 with a size standard 500 employees. Based on the responses received from this SOURCES SOUGHT announcement, the proposed acquisition may be solicited as a Total Small Business Set-Aside. All eligible small business concerns responding to this Sources Sought Announcement must have the capabilities to provide goods and services as stated below. Procurement : 1. HiSeq 2500, Catalog Number: SY-401-2501, Quantity: One (1). (Must be compatible with the MiSeq, Cbot Cluster, Genome AnalyzerIIx and the HiSeq 2000) 2. Shipping and Insurance. STATEMENT OF WORK: Background : The National Institute of Health (NIH), National Human Genome Research Institute (NHGRI), NIH Intramural Sequencing Center (NISC) is a high-throughput sequencing center supporting all institutes within the NIH. NISC has served the NIH community for over 15 years as a source for high-quality large-scale sequencing and analysis. As next generation sequencing applications expand, so does the demand for NISC services. NISC currently has three (3) MiSeq Systems, three (3) Illumina's Genome Analyzer (GA) IIx, and three (3) HiSeq 2000 Systems which are proven platforms for genetic analysis and functional genomics. This instrument's parallel sequencing technology leverages clonal cluster formation and proprietary reversible terminator chemistry to give it the speed and reduce the cost of large-scale sequencing to generate billions of bases of high-quality DNA sequence per run. The HiSeq 2500 System provides ultra-high output and speed. In a single run one is able to sequence more than 5 human genomes at ~30x coverage. The HiSeq 2500 system is able to process a diverse set of samples within one flow cell, and with the highest data quality currently available. Another key factor in this selection is that this instrument is able to run in an alternate rapid mode which would allow the researchers to decrease turnaround time by many weeks. This is a critical consideration for projects impacting patient diagnosis. The HiSeq 2500 can be switched between a high throughput mode and rapid turnaround run mode. In high throughput run mode, similar to the HiSeq 2000, the HiSeq 2500 enables sequencing of a large number of genomes, exomes, or transcriptomes in a single run, allowing large studies to be completed with the fewest number of runs. In rapid run mode, the HiSeq 2500 is capable of sequencing a 30x genome in a day or completing fast multiplexed applications such as exome resequencing or RNA Seq. The rapid run time includes automated, on-instrument cluster generation, and paired-end sequencing, with no user intervention needed throughout the entire process. The HiSeq 2500 also allows researchers to process samples by a single method that is compatible with HiSeq 2000 and HiSeq 2500. This simplifies the NISC lab processes, minimizing labor and equipment costs, and gives researchers the flexibility to route samples to either machine type depending on the needs of the project and machine availability. The high speed of the HiSeq 2500, means that reagents sit out for a shorter period of time and decay to a lesser degree during the run. The result is longer, more accurate reads (300 vs 200 bases). This allows NISC to expand the sequencing applications supported on this platform, as some supplications require longer reads. Contractor Requirements : • Must be able to run the same chemistry as Illumina's HiSeq 2000, MiSeq, and Genome Analyzer IIx Systems. • Run time for 200 base run must be under 30 hours. • Data should be able to be processed through NISC's data analysis software. • Preparation time for samples to load on the sequencer should take about a day. • Read length at least 150 bp. • Produce paired-end reads of 60 million per run. • Reagents are in convenient volumes and are ready-to-load. • Oil is not required for the optics. • Straightforward protocols that require no beads or emulsions. • System should be able to perform amplification, sequencing and data analysis in one unit. Government Responsibilities : Not applicable Reporting Requirements and Deliverables : Not Applicable Program Management and Control Requirements: Not applicable Inspection and Acceptance Requirements : • Upon arrival of equipment to destination, the package must be undamaged. • In the installation of the equipment, all parts including computer must be functional and running in proper order. Interested qualified small business organizations should submit a tailored capability statement for this requirement, not to exceed 20 single-sided pages (including all attachments, resumes, charts, etc.) presented in single-space and using a 12-point font size minimum, that clearly details the ability to perform the aspects of the notice described above and in the draft SOW. All proprietary information should be marked as such. Statements should also include an indication of current certified small business status; this indication should be clearly marked on the first page of your capability statement (preferably placed under the eligible small business concern's name and address). Responses will be reviewed only by NIH personnel and will be held in a confidential manner. All capability Statements sent in response to this SOURCES SOUGHT notice must be submitted electronically (via email) to Dorothy Maxwell, Contract Specialist, at maxwelld@mail.nih.gov in either MS Word or Adobe Portable Document Format (PDF), by February 15, 2013 7:30 AM, EST. All responses must be received by the specified due date and time in order to be considered.
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/NIH/NHLBI/HHS-NIH-NHLBI-CSB-(HG)-2013-084-DLM/listing.html)
- Place of Performance
- Address: NIH, Rockville, Maryland, 20852, United States
- Zip Code: 20852
- Zip Code: 20852
- Record
- SN02979186-W 20130206/130204234351-87b732d726189b743e883d291d8b03c3 (fbodaily.com)
- Source
-
FedBizOpps Link to This Notice
(may not be valid after Archive Date)
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