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FBO DAILY ISSUE OF JULY 16, 2011 FBO #3521
SOURCES SOUGHT

66 -- ArrayScan VTI HCS Reader

Notice Date
7/14/2011
 
Notice Type
Sources Sought
 
NAICS
334516 — Analytical Laboratory Instrument Manufacturing
 
Contracting Office
Department of Health and Human Services, National Institutes of Health, National Heart, Lung and Blood Institute, Rockledge Dr. Bethesda, MD, Office of Acquisitions, 6701 Rockledge Dr RKL2/6100 MSC 7902, Bethesda, Maryland, 20892-7902
 
ZIP Code
20892-7902
 
Solicitation Number
NHLBI-CSB-(HG)-2011-263-JML
 
Archive Date
8/4/2011
 
Point of Contact
Jonathan M. Lear, Phone: 3014514470
 
E-Mail Address
learj@nhlbi.nih.gov
(learj@nhlbi.nih.gov)
 
Small Business Set-Aside
N/A
 
Description
This Sources Sought (SS) Notice is for information and planning purposes only and shall not be construed as a solicitation or as an obligation on the part of the National Heart, Lung, and Blood Institute (NHLBI) on behalf of the National Human Genome Research Institute (NHGRI). The purpose of this SS is to identify qualified small business concerns, including Small Disadvantaged Businesses (SDB), Woman-Owned Small Businesses (WOSB), Historically Underutilized Business Zone (HUBZone) Small Businesses, Veteran-Owned Small Businesses (VOSB), and Service-Disabled Veteran-Owned Small Businesses (SDVOSB) that are interested in and capable of providing an ArrayScan VTI HCS Reader - LED Based System in accordance with the below specifications. The NHLBI does not intend to award a contract on the basis of responses nor otherwise pay for the preparation of any information submitted. As a result of this Sources Sought notice, the NHLBI may issue a Request for Quote (RFQ). THERE IS NO SOLICITATION AVAILABLE AT THIS TIME. However, should such a requirement materialize, no basis for claims against NHLBI shall arise as a result of a response to this Sources Sought notice or the NHLBI's use of such information as either part of our evaluation process or in developing specifications for any subsequent requirement. The NHLBI is seeking capability statements from all eligible small business concerns, particularly Small Disadvantaged Businesses (SDB), Woman-owned Small Businesses (WOSB), Historically Underutilized Business Zone (HUBZone) Small Businesses, Veteran-Owned Small Businesses (VOSB), and Service-Disabled Veteran-owned Small Businesses (SDVOSB) under the North American Industry Classification System (NAICS) code 334516 with a size standard of 500. Based on the responses received from this SOURCES SOUGHT announcement, the proposed acquisition may be solicited as a Total Small Business Set-Aside. All eligible small business concerns responding to this Sources Sought announcement must have the capabilities to provide the below product within 4-6 weeks after receipt of purchase order. Background Information The mission of the NIH Chemical Genomics Center (NCGC), a branch of the National Center for Translational Therapeutics (NCTT), is to apply the tools of small molecule screening and discovery to the development of chemical probe research tools, for use in the study of protein and cell functions, and biological processes relevant to physiology and disease. This request will enable the NCGC and the Tox21 project to increase the capability to optimize biochemical, cellular, and model organism-based assays submitted by the biomedical research community; perform automated high-throughput screening (HTS); and perform chemistry optimization on confirmed hits to produce chemical probes for dissemination to the research community. The Tox21 program is part of the NCTT. One goal of the Tox21 program is to incorporate and develop High Content Screens (HCS) in parallel and/or, in conjunction with, the Center's well-established quantitative High Throughput Screens (qHTS) for cell-based toxicity. HCS will enable confirmation of true positive hits obtained from the qHTS. HCS allows you to acquire spatially and/or temporally resolved information on a biological event and automatically quantify the results. Below are the Government required specifications for the ArrayScan VTI HCS Reader: Specifications -ArrayScan VTI HCS Reader: oFully automated Axio Observer Z1 optical bench; oAutomated Stage with plate insert; oHigh-resolution, shutterless cooled CCD camera; o5X Fluar, 10X Plan NeoFluar, 10X Plan Apochromat, 20X Achroplan Objectives; oOptimal filters for blues (Hoechst), greens (FITC, GFP), orange reds (TRITC), deep reds (Texas Red), and long reds (Cy5); o1x coupler; oFive color, direct coupled, Light Emitting Diode (LED); and, oLaser scanning barcode reader. -ArrayScan Instrument Computer: oIntel Quad-core, 2GHz each; o4GB RAM; o2HDD (146GB each); o256MB video card; o16X CD/DVD R/W Drive; o20" high-resolution LCD flat-panel monitor; and oArrayScan NCS Reader Software for scanning and quantitative cell analysis, autofocus, auto exposure, and cell subpopulation analysis tools. -Bioapplications include: oTarget Activation V4; Cell Cycle V4; Cell Health Profiling V4; Cell Motility V4; Cell Spreading V4; Colocalization V4; Comet Assay V4; Compartmental Analysis V4; Cyto-Cell Membrane Translocation V4; Cyto-Nuc Translocation V4; Cytotoxicity V4; GPCR Signaling V4; Micronucleus V4; Molecular Translocation V4; Morphology Explorer V4; Neurite Outgrowth V4; Neuronal Profiling V4; Spot Detector V4; Tube Formation V4; and Zebratox V4. -Desktop Software: oTwo (2) copies of vHCS View desktop HCS visualization software; oOne (1) copy of vHCS Discovery ToolBox-Platinum Edition (x.6 systems); oiDev Intelligent Assay Development workflow software; and, oiView Image Browser to access cell, field, well, and plate images. Interested parties should submit a tailored capability statement for this requirement, not to exceed 10 single-sided pages (including all attachments) presented in single-space and using a 12-point font size minimum, that clearly details the ability to provide this equipment. Statements should also include an indication of current certified small business status; this indication should be clearly marked on the first page of your capability statement (preferably placed under the eligible small business concern's name and address). Responses will be reviewed only by NIH personnel and will be held in a confidential manner. All capability statements sent in response to this SOURCES SOUGHT notice must be submitted electronically (via email) to Jonathan Lear, Contract Specialist, at learj@nhlbi.nih.gov in either MS Word or Adobe Portable Document Format (PDF), by July 20, 2011, 12:00pm, EST. All responses must be received by the specified due date and time in order to be considered.
 
Web Link
FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/NIH/NHLBI/NHLBI-CSB-(HG)-2011-263-JML/listing.html)
 
Place of Performance
Address: National Institutes of Health/NHGRI, Bethesda, Maryland, 20892, United States
Zip Code: 20892
 
Record
SN02499554-W 20110716/110714235836-0d99d0b64d9484bb81366bcabe6bf909 (fbodaily.com)
 
Source
FedBizOpps Link to This Notice
(may not be valid after Archive Date)

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