SOURCES SOUGHT
88 -- Iinbre Targeted Mutations Strain Mice
- Notice Date
- 7/12/2011
- Notice Type
- Sources Sought
- NAICS
- 112990
— All Other Animal Production
- Contracting Office
- Department of Health and Human Services, Food and Drug Administration, Office of Acquisitions and Grants Services, 5630 Fishers Lane, Room 2129, Rockville, Maryland, 20857-0001
- ZIP Code
- 20857-0001
- Solicitation Number
- 1090400
- Archive Date
- 7/30/2011
- Point of Contact
- Howard Nesmith, Phone: 870-543-7459
- E-Mail Address
-
howard.nesmith@fda.hhs.gov
(howard.nesmith@fda.hhs.gov)
- Small Business Set-Aside
- N/A
- Description
- MARKET RESEARCH PURPOSES ONLY NOT A REQUEST FOR PROPOSAL OR SOLICITATION Small And Any Other Size Business Are Encouraged To Respond The U.S. Food and Drug Administration (FDA), Jefferson Laboratories, in Jefferson, Arkansas, is conducting market research to support the Center for Biologics Evaluation and Research (CBER). CBER research and regulatory scientists routinely use a wide variety of targeted mutant mouse strains in laboratory investigations, many of which are either bred at CBER or ordered from a supplier. The vast majority of mice bearing such targeted mutations have been inbred onto either C57BL/6J (Jackson strain) black mouse or BALB/cByJ (Jackson strain) white mouse genetic backgrounds; that is, they are bred to be genetically identical to the normal mice in all respects except for the targeted mutation of interest. The studies in which these mice are used require considerably larger numbers of "control" normal C57BL/6J and BALB/cByJ wild type mice as points of comparison, with consistent and predictable supplies of the appropriately age and gender matched mice. Entering into an agreement with predictable dates of delivery of specified numbers of normal mice allows investigators to establish in-house breeding schedules and colony sizes to match normal mice whose availability is ensured. Similarly, entering into an agreement allows the supplier to adjust their normal C57BL/6J and BALB/cByJ breeding colony stock as needed to meet CBER's established, predictable demand. Similarly, many of the rare knockout strains, such as the B6.129S6-Tbx21tm1Glm/J and B6.129S1-Il12btm1Jm/J strains requested here, are only available sporadically and in small numbers, but entering a service agreement request allows the supplier to increase their normal breeding colony stock to meet CBER's demand on a predictable and consistant schedule. Item #1 Quantity of 1,720 C57BL/6J, strain # 000664 male mice at 4 weeks of age Item #2 Quantity of 760 BALB/cByJ strain # 001026 male mice at 5 weeks of age Item #3 Quantity of 160 B6.129S6-Tbx21<tm1Glm>/J HOM Homozygous for Tbx21<tm1Glm> strain # 004648 male mice any age Item #4 Quantity of 160 Strain # 002693 B6.129S1-Il12b<tm1Jm>/JHOM Homozygous for Il12b<tm1Jm> male mice at 6-8 weeks Item #5 Shipping will consist of 178 Shipping crates and 178 Shipments of 20 animals per container Firms believing they offer an equivalent strain of mice as identified above are encouraged to respond electronically via email to the attention of Howard Nesmith at howard.nesmith@fda.hhs.gov on or before July 15, 2011 by 9:00 AM (Central Time) with no less than the following information: • Business name, DUNS number, business address, business website, business size status (i.e., SB, VOSB, SDVOSB, HUBZone SB, SDB, WOSB, LB), point of contact name, mailing address (if different from business address), phone number and email address; [North American Industry Classification System (NAICS) Code is 112990 - All Other Animal Production. Small Business Size Standard is $0.75 in millions of dollars. • Sufficient descriptive literature that unequivocally demonstrates that offered products meet or exceed above specifications. • Though this is not a request for quote, informational pricing may be submitted. The government is not responsible for locating or securing any information, not identified in the response. For information regarding this market research effort, please contact Howard Nesmith at howard.nesmith@fda.hhs.gov. Disclaimer and Important Notes This notice does not obligate the Government to award a contract or otherwise pay for the information provided in response. The Government reserves the right to use information provided by respondents for any purpose deemed necessary and legally appropriate. Any organization responding to this notice should ensure that its response is complete and sufficiently detailed to allow the Government to determine the organization's qualifications to perform the work. Respondents are advised that the Government is under no obligation to acknowledge receipt of the information received or provide feedback to respondents with respect to any information submitted. After a review of the responses received, a pre-solicitation synopsis and solicitation may be published in FedBizOpps. However, responses to this notice will not be considered adequate responses to a solicitation. Confidentiality No proprietary, classified, confidential, or sensitive information should be included in your response. The Government reserves the right to use any non-proprietary technical information in any resultant solicitation(s). Notice of Intent In the event no responses (included no acceptable response) received to this market research effort this will serve as the notice effort to enter into a sole source contract with The Jackson Laboratory for their genetically manipulated mice.
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/FDA/DCASC/1090400/listing.html)
- Place of Performance
- Address: U.S. Food and Drug Administration, 11400 Rockville Pike, Rockville, Maryland, 20857, United States
- Zip Code: 20857
- Zip Code: 20857
- Record
- SN02495539-W 20110714/110712234405-2f4436ad0b26278d835f1f6e0f5f5f3f (fbodaily.com)
- Source
-
FedBizOpps Link to This Notice
(may not be valid after Archive Date)
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