SOURCES SOUGHT
65 -- Real-time Autoradiography Equipment
- Notice Date
- 6/2/2011
- Notice Type
- Sources Sought
- NAICS
- 339112
— Surgical and Medical Instrument Manufacturing
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, Clinical Center/Office of Purchasing & Contracts, 6707 Democracy Blvd, Suite 106, MSC 5480, Bethesda, Maryland, 20892-5480
- ZIP Code
- 20892-5480
- Solicitation Number
- P11-004706
- Archive Date
- 6/21/2011
- Point of Contact
- Gail Akinbinu, Phone: 301-496-0692
- E-Mail Address
-
gakinbinu@cc.nih.gov
(gakinbinu@cc.nih.gov)
- Small Business Set-Aside
- N/A
- Description
- The National Institutes of Health, Clinical Center is conducting a market survey/sources sought to help determine the availability and technical capability of qualified small businesses, veteran-owned small businesses, service disabled veteran-owned small businesses and/or HUBZONE small business capable of serving the needs mentioned below. This market survey/sources sought announcement is not a request for proposals and the Government is not committed to award a contract pursuant to this announcement. The information from this market research is for planning purposes only and will assist the Government in planning its acquisition strategy. This is strictly market research and the Government will not entertain questions concerning this market research. The Government will not pay for any costs incurred in the preparation of information for responding to this market survey. The North American Industry Classification System (NAICS) code is 339112, Size Standard - 500 employees. The National Institutes of Health Radiology & Imaging Sciences Department intends to procure an advanced autoradiography technology using real-time imaging and multilabeling patent owned by Biospace. These technologies will be used for applications in imaging rat brains using various tracers. This will be the pre-PET imaging applications for those unique stracers and fast acquistion of autoradiographic imagin becomes of utmost importance, as well as the real-time application as nobody knows yet the exposure time necessary for our study specimen. This equipment is needed to start an autoradiography service for the Hammoud lab, which is a new lab dedicated to imaging of infectious diseases. Autoradiography will help determine the tissue distributions of inflammation and infection-associated receptors and cells both in vivo and in vitro. We have reviewed multiple other options for autoradiography however none of the other instruments can provide the following two characteristics: 1. Real-time acquisition of data which means that every disintegration will be seen, measured and listed in the image file with a number of criteria (time of occurrence, size, shape, brightness) allowing the discrimination of 2 to 3 different isotopes in the same experiment based on the difference of Energy or Decay. This opens the way to unlimited applications referred to as Multi-labeling. In addition, this system’s characteristic allows fast and high resolution acquisition of the data, without the risk of over or under-exposure which can sometimes lead to failed studies and necessitate repeating the experiments. We hope this will result in a more accurate evaluation of the receptors, using a smaller number of animals. 2. Multi-labeling: This is a method of generating a plurality of images of a substrate from radioactive radiation coming from a plurality of radioactive tracers contained in the substrate. To this end, data representing the different detection signals generated by a detector are memorized, individually for each radioactive emission detected during a certain observation period, then statistical processing of these data is carried out in such a way as to estimate the images of the different tracers which correspond best to the set of memorized data. This will allow us to track more than one target in the same sample of animals. Biospace owns the patent for this technology. When compared to other systems, this system also provides higher resolution and faster acquisition times than phosphor imagers. The resolution using films is still better however this technique is becoming obsolete and soon there won’t be any market for it. In addition, we do not have access to a dark room in order to process the films. For all these reasons, we believe the micro-imager fits our needs perfectly and we believe it will allow us to perform state-of-the-art autoradiography experiments. Vendors must submit capabilities statement to Gail Akinbinu at the following email address: gakinbinu@cc.nih.gov. Please submit documentation no later than June 6,201110A.M.
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/NIH/CCOPC/P11-004706/listing.html)
- Place of Performance
- Address: 9000 Rockjville Pike, Bethesda,, Maryland, 20892, United States
- Zip Code: 20892
- Zip Code: 20892
- Record
- SN02462304-W 20110604/110602234540-07ed43f8f41534b27d39b6e6f1f46a36 (fbodaily.com)
- Source
-
FedBizOpps Link to This Notice
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