SOLICITATION NOTICE
A -- Cancer Prevention Agent Development Program: Early Phase Clinical Research
- Notice Date
- 3/4/2011
- Notice Type
- Presolicitation
- NAICS
- 541712
— Research and Development in the Physical, Engineering, and Life Sciences (except Biotechnology)
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Cancer Institute, Office of Acquisitions, 6120 Executive Blvd., EPS Suite 600, Rockville, Maryland, 20852
- ZIP Code
- 20852
- Solicitation Number
- N01CN05014-69
- Point of Contact
- Donna M Perry-Lalley, Phone: (301) 435-3776, Virginia DeSeau, Phone: 301-435-3798
- E-Mail Address
-
perryd@mail.nih.gov, deseauv@mail.nih.gov
(perryd@mail.nih.gov, deseauv@mail.nih.gov)
- Small Business Set-Aside
- N/A
- Description
- Pre-Solicitation Request for Proposals (RFP) N01CN05014-69, Cancer Prevention Agent Development Program: Early Phase Clinical Research Contracting Office Address Department of Health and Human Services, National Institutes of Health (NIH), National Cancer Institute (NCI), Office of Acquisitions, 6120 Executive Boulevard, Suite 600, Room 6002, Bethesda, MD 20892-7195. Note: This synopsis follows a Sources Sought notice that was released on February 12, 2010 under HHS-NIH-NCI-PCPSB-5014-29 Description The National Institutes of Health (NIH), National Cancer Institute (NCI), Division of Cancer Prevention (DCP), Phase I/II Cancer Prevention Clinical Trials Program is seeking proposals from qualified organizations who have the capacity to conduct early phase clinical trials and accrue a specified number of subjects per year. The main objective of the contracts awarded as a result of the solicitation will be the conduct of multiple early phase clinical trials to rapidly evaluate the clinical activity and biologic effects of cancer preventive agents. The contracts will provide essential clinical trials infrastructure and laboratory support: (1) To efficiently design and conduct early phase clinical trials of cancer preventive agents of various classes; (2) To characterize the biological effects of new cancer preventive agents on their defined molecular targets as well as on multiple endpoints associated with carcinogenesis and correlate these effects with clinically relevant endpoints; and (3) To develop scientific insights into the mechanisms of cancer prevention by the agents examined and to continue to develop novel potential markers as determinants of response. Each Contractor shall be able to initiate multiple clinical trials per year accruing a minimum of 75 total study participants to Phase 0 - Phase II clinical trials, with the emphasis on Phase II trials. The agents to be studied will be DCP-specified cancer preventive agents as well as agents obtained by the Contractor. The size of each trial will vary depending on phase of development and organ site. However, each Contractor shall have the capacity to perform studies in multiple organs (i.e., more than 2) and is strongly encouraged to establish an infrastructure composed of one or more collaborating institutions to enhance their capability to conduct these clinical trials and to provide specific technical expertise for biomarker studies. The proposed acquisition will be a full and open competition. The contracts for the project are currently held by: Institution and Contract Number- University of Arizona, Tucson, AZ N01-CN-35158 University of California-Irvine, Orange, CA N01-CN-35160 Northwestern University, Chicago, IL N01-CN-35157 Mayo Clinic Foundation, Rochester, MN N01-CN-35000 University of Texas M. D. Anderson Cancer Center, Houston, TX N01-CN-35159 University of Wisconsin-Madison, Madison, WI N01-CN-35153 The North American Industry Classification System (NAICS) code is 541712. The NCI intends to award multiple cost reimbursement type contracts for a base period of five years plus two, one year options on or about June 2012. Request for Proposal number N01CN05014-69 will be available on or about March 21, 2011, with a due date for receipt of proposals on or about July 21, 2011. POTENTIAL OFFERORS WILL BE RESPONSIBLE FOR DOWNLOADING THEIR OWN COPY OF THE SOLICITATION AND AMENDMENTS. ALL INQUIRIES SHALL BE SUBMITTED ELECTRONICALLY TO THE CONTRACTING OFFICER LISTED AS THE POINT OF CONTRACT HEREIN.
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/NIH/RCB/N01CN05014-69/listing.html)
- Record
- SN02394208-W 20110306/110304234713-063526a4a86f1e1a7363f59c52352fce (fbodaily.com)
- Source
-
FedBizOpps Link to This Notice
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