SOLICITATION NOTICE
A -- Detection of Bacterial Biothreat Agents and Toxins - BAA 11-01
- Notice Date
- 10/20/2010
- Notice Type
- Combined Synopsis/Solicitation
- NAICS
- 541711
— Research and Development in Biotechnology
- Contracting Office
- Office of the Chief Procurement Officer, Washington, District of Columbia, 20528, United States
- ZIP Code
- 20528
- Solicitation Number
- BAA11-01
- Point of Contact
- Susan Eicher,
- E-Mail Address
-
susan.eicher@dhs.gov
(susan.eicher@dhs.gov)
- Small Business Set-Aside
- N/A
- Description
- Appendices B and C (WORD Format) BAA 11-01(PDF) This Broad Agency Announcement (BAA11-01) seeks research and development proposals for the purposes of producing highly specific, robust, and accurate lateral flow immunoassays (LFA) for the detection of bacterial biothreat agents and toxins. These assays are intended for use by the First Responder community for the detection and identification of bacterial biothreat agents and toxins present in "white powder" samples, and other suspected material encountered by the First Responder community. The creation of such assays include establishing the protocol for sample preparation or recovery, all extraction methods, performance of the actual analysis of the antigenic signature of the agents from their associated samples using LFA, unambiguous interpretation of results (i.e., positive or negative). Lateral flow immunoassay systems are fundamentally immunoassays adapted to function along a single axis or test strip format. A typical double antibody capture assay system consists of several components. These assays can be interpreted visually, or by utilizing specialized instruments or readers. 1. The sample pad - an absorbent pad onto which the analyte is applied. 2. Conjugate or reagent pad - to which specific antibodies to the analyte are conjugated to colored particles (usually colloidal gold particles, or latex microspheres). 3. Reaction membrane - usually hydrophobic nitrocellulose or cellulose acetate membrane onto which specific antibodies to the analyte are immobilized in a line across the membrane as a capture zone or test line; (a control zone may also be present, containing antibodies specific for the conjugate antibodies). 4. Wick or waste reservoir - an absorbent pad designed to draw the sample across the reaction membrane by capillary action and collect it. 5. A method of collecting the sample is considered part of the assay system.
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/DHS/OCPO/DHS-OCPO/BAA11-01/listing.html)
- Place of Performance
- Address: To Be Determined at Contract Award, United States
- Record
- SN02314057-W 20101022/101020234125-3bc3bdab5ffc15b2069f1271ee1724d9 (fbodaily.com)
- Source
-
FedBizOpps Link to This Notice
(may not be valid after Archive Date)
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