MODIFICATION
A -- NHLBI DNA Resequencing and Genotyping (RS&G) Service: Administrative Coordinating Center
- Notice Date
- 3/1/2010
- Notice Type
- Modification/Amendment
- NAICS
- 541712
— Research and Development in the Physical, Engineering, and Life Sciences (except Biotechnology)
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Heart, Lung and Blood Institute, Rockledge Dr. Bethesda, MD, Office of Acquisitions, 6701 Rockledge Dr RKL2/6100 MSC 7902, Bethesda, Maryland, 20892-7902
- ZIP Code
- 20892-7902
- Solicitation Number
- NHLBI-HV-11-20
- Archive Date
- 3/30/2010
- Point of Contact
- Christopher Schaupp, Phone: (301) 435-0340, Joanne F Deshler, Phone: (301) 435-0340
- E-Mail Address
-
cschaupp@nhlbi.nih.gov,
(cschaupp@nhlbi.nih.gov, ontracting)
- Small Business Set-Aside
- N/A
- Description
- (THE PURPOSE OF THIS MODIFICATION IS TO CHANGE THE RESPONSIBLE POINT OF CONTACT TO CHRISTOPHER SCHAUPP. THE ORIGINAL POST DATE OF 2/4/2010 REMAINS IN EFFECT) The National Heart, Lung, and Blood Institute (NHLBI) is seeking an Administrative Coordinating Center for the NHLBI DNA Resequencing and Genotyping Service. THIS IS A SYNOPSIS NOT A SOLICITATION. Background The NHLBI DNA Resequencing and Genotyping (RS&G) Service will provide high quality, high-volume resequencing and genotyping for investigators to discover and type DNA variations needed to elucidate the genetic components involved in the cause, variable outcome and progression of heart, lung, and blood diseases and disorders. The RS&G Service will consist of Laboratory Center(s) capable of performing both massively high throughput, large-scale DNA resequencing and high throughput genotyping for heart, lung, and blood investigators; and one Administrative Coordinating Center (ACC) to provide the logistical support for the entire RS&G Service. Laboratory Center(s) will be awarded under a separate solicitation. Project Requirements The ACC serves as the focal point for coordination of the various elements of the RS&G Service. Specifically, the ACC shall maintain the website, advertise and market the RS&G Service to the research communities; process the requests for use of the LCs, provide logistical support for the three RS&G Service committees, and facilitate communication among the centers and with NHLBI. During the entire period of performance, the ACC shall coordinate, arrange provide necessary information and materials, and otherwise facilitate meetings and conference calls of the Steering Committee, Evaluation Panel, Oversight Committee, and any other groups determined necessary for the RS&G Service. Prepare and distribute minutes or reports according to the needs and time constraints of each group. During the Transition/Early Production phase (1 to 3 months), the ACC shall: (1)Contribute to and facilitate all aspects of the Steering Committee’s efforts to modify and implement the procedures and processes for the RS&G Service; (2)Develop a Manual of Operations for the Program and related standardized tracking, formats, and reports for management information and for all non-laboratory aspects of RS&G Service operations; (3)Develop and implement effective and efficient communication interfaces for information to and requests from the research community for: •Outreach/Promotion - The Administrative Coordinating Center will inform the research community of the availability of the Laboratory Center(s) and services through advertisement in journals, exhibits at national meetings, and a web site. The current web site (http://RSnG.nhlbi.nih.gov will be fully operational under the new contractor within two months after award. The web site has a public view for visitors to find out about the RS&G Service and for investigators to read about application guidelines and instructions for the application submission process. The web site has a permissions-based modular design that supports various roles (NHLBI staff, Evaluation Panel, Oversight Committee, and Steering Committee) under appropriate credentials. All brochures, advertisements, marketing strategies, the exhibit booth design, and web site plans must be approved in advance by the NHLBI Contracting Officer’s Technical Representative (COTR). •Applications/Processing: The ACC shall maintain and enhance existing procedures and formats for information and submission procedures for potential applicants; the ACC shall develop procedures to receive, log, and track the requests from investigators to use the services. Electronic submission will be mandatory. •Evaluation: The ACC will work with the Evaluation Panel to provide requests, schedule Evaluation Panel meetings and conference calls, and uploading of their comments and ranking. •Following the prioritization process and approval by NHLBI, the ACC shall: Track status of approved projects from the data provided by the Laboratory Center and maintain an updated list of the Completed Projects from the data supplied by the Laboratory Center. (4)Develop and implement effective and efficient communication and operational interfaces with Laboratory Center(s), maximizing the use of electronic communications. The ACC shall provide information from RS&G Service committees and panels for Laboratory Center implementation of approved standardization procedures. Implement methodology to track and report assigned work and accomplished work at each Laboratory Center and for the Laboratory Center(s) overall. Receive production, quality control, and other information as needed for the committees, panels, and ACC to fulfill their functions in the RS&G Service. (5)Develop and implement effective and efficient communication and operational interfaces with NHLBI. Keep NHLBI informed by communicating frequently and regularly. Promptly identify to NHLBI any concerns or barriers to performance, thus permitting prompt solutions and maximum effectiveness. •Forward for NHLBI approval recommendations from the committees, panels, and ACC for: Standardization of procedures, communication formats, etc for the ACC and Laboratory Center(s); Applicant priority recommendations and comments from the evaluation Panel; Procedures and timelines for posting information on the web site; and Review comments and recommendations from the Oversight Committee regarding performance of each Laboratory Center and the ACC. •Implement or forward NHLBI approvals or required revisions to the relevant RS&G Service component(s). (6)Implement the following reporting requirements to NHLBI: Submit a monthly summary of the status of studies approved to use the services, of assigned studies, of completed studies, and on web site issues; and submit quarterly progress report. (7)Develop and implement an effective and efficient management information system that provides useful, accurate, and timely reports on program status to NHLBI and to all components of the RS&G Service. (8)Ensure effective and accurate communications with the DNA re-sequencing and genotyping community by applying appropriate technical/scientific expertise to ACC tasks. During Phases II (months 4-36) and III (months 37-60) – the Production and High Production phases the ACC shall: (1)Continue and/or finalize requirements from Transition/Early Production phase. (2)Implement the following reporting requirements to NHLBI: •Submit technical progress report. •On an annual basis, propose a Performance Assessment Scheme (PAS) for the upcoming year. (3) Develop and implement the technical assistance and information sharing aspects of the web site. The information sharing aspects of the web site shall be updated a minimum of once per month. Via the web site, the ACC shall provide public access to a table listing the genes/regions that have been re-sequenced, the investigators who have used the RS&G Service, laboratory information such as laboratory protocols, quality control procedures, quality control data, sample applications, help, answers to frequently asked questions, user-friendly links for reporting problems and asking questions, and other agreed upon materials such as tutorials, site URLs or links for publicly available software for interpreting sequencing data or selecting variants for genotyping. The web site shall offer search capability by genomic region and gene name. (4) Continuously seek and recommend ways to improve the performance by the ACC and by the RS&G Service as a whole. Maintain a partner-focused cooperative working relationship with the Laboratory Center(s), all committees/panels, and the NHLBI. (5) Maintain all databases, website, software, and services in a manner than can be readily transitioned to another provider to ensure continuity of service in the event of contract termination or upon contract re-competition. Cooperate with NHLBI and the new provider in the event of a transition to a new provider. (6)Submit the final report and all products developed under the contract. This is not a request for proposal (RFP) and the Government is not committed to award a contract pursuant to this announcement. It is anticipated that the RFP will be available on FedBizOpps on or about February 20, 2010. This advertisement does not commit the Government to award a contract.
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/NIH/NHLBI/NHLBI-HV-11-20/listing.html)
- Record
- SN02079026-W 20100303/100301234613-7743872926b51be356913d8417e7101a (fbodaily.com)
- Source
-
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