MODIFICATION
66 -- RECOVERY Hamilton MICROPLAB STARlet Automated sample handling system.
- Notice Date
- 2/24/2010
- Notice Type
- Modification/Amendment
- NAICS
- 334516
— Analytical Laboratory Instrument Manufacturing
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Cancer Institute, Office of Acquisitions, 6120 Executive Blvd., EPS Suite 600, Rockville, Maryland, 20852
- ZIP Code
- 20852
- Solicitation Number
- RFQ-NCI-100004-2010-NG
- Archive Date
- 3/18/2010
- Point of Contact
- Malinda L Holdcraft, Phone: (301) 402-4509, Caren N Rasmussen, Phone: (301) 402-4509
- E-Mail Address
-
holdcram@exchange.nih.gov, cr214i@nih.gov
(holdcram@exchange.nih.gov, cr214i@nih.gov)
- Small Business Set-Aside
- Total Small Business
- Description
- RECOVERY: Notice amended on February 24, 2010 to reflect "to procure the BRAND NAME - Hamilton Company and to add BRAND NAME Justification. RECOVERY: The National Cancer Institute (NCI), Center for Cancer Research, Laboratory of Metabolism (LM) plans to procure the BRAND NAME - Hamilton Company MICROLAB STARlet. This acquisition will be processed under FAR Part 12 Acquisition for Commercial Items and will be made pursuant to the authority in FAR 13.106-1(b)(2) and 13.501-(a)(1) using simplified acquisition procedures for commercial acquisitions. The North American Industry Classification System Code is 334516 and the business size standard is 500 employees. This is a 100 percent small business set aside. Only one award will be made as a result of this solicitation. This will be awarded as a firm fixed price type contract. Delivery be one to two weeks upon receipt of award. Contractor Requirements: Contractor shall provide one Hamilton MICROLAB STARlet, parts and accessories, and software. The instruments shall include the following characteristics as these are vital aspects to the NCI. a) Air Displacement Pipetting Channels: shall have air-displacement technology, which is analogous to a hand held electronic pipette. The benefits of this technology include the following: In combination with disposable tips, the risk of contamination of critical assays is reduced to an absolute minimum. High accuracy and precision from sub-microliter volumes to 1 ml can be reached with the same pipetting channels. No system liquid, diluters, valves or complicated tubing is required. No dilution effects of samples with system fluid. Each channel has a pressure monitoring system to monitor pipetting steps. b) Monitored Air Displacement (MAD): shall have air-based pipetting action, the instrument detects clots or empty wells during the aspiration step in real time. Thus monitored air displacement eliminates uncertainty in automated assays by providing reliable, consistent walk-away automation; shall have anti-droplet control (ADC) that compensates for pressure changes in the channels that are caused by the high vapor pressure of volatile solvents in real time. This allows accurate pipetting of highly volatile solvents that would otherwise prevent automation of assays involving robots for this purpose. c) Compression induced O ring expansion (CORE) disposable technology: the CORE system attaches disposable tips to the pipetting channels by mechanically expanding an O-ring into a channel inside the tip. This enables a precision of ±0.1 mm on all axes with respect to the tip position during all pipetting steps. The system requires no vertical force for tip attachment or tip ejection, thus eliminating mechanical stress and improving the overall system reliability and reproducibility. The CORE system also enables the user to confirm the size of the tip being used and also run a quick seal verification test, prior to each run to insure that O-ring integrity and seal are intact to avoid leaks during the course of the experiment. d) I-SWAP: an internal robotic gripping arm that can operate on the same arm as the pipetting channels. This allows for a much larger working envelope than a separate arm system design. Since the I-SWAP inherently knows where everything is positioned on the deck based on the input method it saves user time in setting up methods or creating new ones. The I-SWAP also has grip detection system and can reach on both sides of the system deck allowing more flexibility and upgradeability for adding additional peripherals to the system. e) Liquid level detection shall offer 3 modes of liquid level detection: Capacitance Liquid Level Detection (CLLD) each channel operates on its own frequency, minimizing the chances of false detection caused by interference. This creates a more robust system and averts errors. Pressure Liquid Level Detection (PLLD) each channel has its own pressure transducer and can monitor the pressure change in the tip to detect liquid. This is used for non-ionic liquids and offers the user more control over all liquids pipetted by the system. CLLD & PLLD the two modes of liquid level detection can be used in combination on any step and can provide true liquid extraction (LLE) functionality. f) 96 tip pipette head - volume range of 1ul to 1mL. Also offers CLLD on two channels for better reproducible pipetting performance. g) Barcode reader- The auto loader barcode reader offers sample identification confirmation for all pipetting steps. It also confirms the correct carriers and lab-ware based on the method the user is running and also offers a continuous feed option to increase the systems overall throughput. h) Software shall offer an easy to use interface while still providing complete control over the system. There are multiple wizards available to allow the user to quickly set up standard pipetting routines. The software shall offer an export package feature which assists remote access and troubleshooting by the vendor technical support. Contractor shall be responsible for installation and training of this instrument. BRAND NAME JUSTIFICATION: The Laboratory of Metabolism (LM), Center for Cancer Research, NCI, is requesting a MICROLAB STARlet Automated sample handling system from Hamilton Company. This system will allow the LM to enhance its participation in the Metabolomics program, within the NCI, to discover, develop (and license) novel small molecule biomarkers for cancer, toxicity, radiation exposure and other diseases. The discovery of biomarkers is a given samples it sometime exhibited by only a subtle, minute yet significant change between a control and treated sample. Because of this, sample preparation process must be consistent and standardized, to prevent false positives from occurring because of inconsistent handling. The Microlab STARlet robotic sample handling station from Hamilton Company offers a versatile instrument with high-throughput automation associated with sample preparation as well as many integrated processes designed to ensure the most accurate, precise and reproducible results obtainable in pipetting systems. A number of inherent features are provided. These include ease and flexibility of use, unique software features such as protocol debugging, file management and system interface capabilities, precise liquid level detection using capacitance for conductive liquids and the pressure signal detection method for non-conductive organic solvents. The STAR robot arm has a monolithic pipette head which is used to perform many pipetting tasks one 96 well at a time with great precision and reproducibility due to accurate disposable tip placement. The Hamilton STAR system will provide more advanced technology and process control features which are patented and are not available on other systems. These features are described above. Potential offerors may request a copy of the solicitation from Malinda Holdcraft, Contract Specialist via electronic mail at holdcram@exchange.nih.gov or fax 301-402-4513. If you have questions regarding this notice, they may be addressed to the aforementioned individual above. When submitting your request, please include complete mailing address, DUNS number, point of contact name, email address, phone and fax numbers. Estimated issue date of the solicitation is February 16, 2010 with an estimated due date of March 1, 2010. No collect calls will be accepted. In order to receive an award, contractor must be registered in and have valid certifications in the Central Contractor Registration (CCR) and the Online Representations and Certifications Application (ORCA). Reference: RFQ-NCI-100004-2010-NG on all correspondence.
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