SPECIAL NOTICE
66 -- Sole source purchase of SpectraMax® M2 Multimode Plate Reader
- Notice Date
- 7/22/2009
- Notice Type
- Special Notice
- NAICS
- 334516
— Analytical Laboratory Instrument Manufacturing
- Contracting Office
- Department of Agriculture, Office of Procurement and Property Management, Procurement Operations Division, 300 7th Street, S.W., Room 377, Reporters Building, Washington, District of Columbia, 20024
- ZIP Code
- 20024
- Solicitation Number
- 299143
- Archive Date
- 8/18/2009
- Point of Contact
- Carol R. Dingess, Phone: 6123363208
- E-Mail Address
-
Carol.Dingess@aphis.usda.gov
(Carol.Dingess@aphis.usda.gov)
- Small Business Set-Aside
- N/A
- Description
- The U.S. Department of Agriculture, Animal Plant Health Inspection Services, Veterinary Services Facility in Ames, IA intends to award a sole source purchase order to Molecular Devices Corp. for a SpectraMax® M2 Multimode Plate Reader. The rationale for this intention to Sole Source can be found in FAR 6.302-1 ( Only one responsible source and no other supplies or services will satisfy agency requirements. ) The SpectraMax M2 is the only microplate reader which has been found to meet all of the following performance specifications needed: Must be a Dual Monochromator-based system for dual mode (fluorescence & absorbance) reading in cuvette port and in 6- to 384- well microplate. Must read absorbance in standard, commercially-available cuvettes and microcuvettes, 12 x 75 mm test tubes, and 96- or 384-microplates with a built-in cuvette port and a microplate drawer in the reader and performed with a single wavelength selection. Must use a Xenon flash lamp for longer lamp lifetime. Must have Dual Monochromators for tunable fluorescence wavelength selection between 250 nm and 850 nm for excitation wavelengths and 360 nm to 850 nm for emission wavelengths. No wavelength filters are required for purchase when additional assays are added to laboratory. Must have tunable absorbance wavelength selection between 200 nm and 1000 nm. No filters are required for purchase in the future when additional assays are added to laboratory. Must have a 4 nm absorbance bandwidth for superior peak resolution and increased accuracy of measurements for narrow bandwidth samples. Must have fixed fluorescence spectral bandwidth of 9 nm EX/EM for improved resolution between excitation and emission. Narrow bandwidth is critical when designing multi-fluorophore assays or when using narrow Stokes shift fluorophores. Must read up to four EX/EM wavelength pairs per microplate for multi-fluorophore assay design. Must have full wavelength scanning capability across the entire spectral range for defining actual EX and EM maxima. Can perform spectral scans in user-defined increments as small as 1 nm, and then can select assay wavelengths for actual maxima. Increases sensitivity for assay by working at actual conditions rather than using literature references. Must have Automatic PMT setting to adjust the optimum voltage for each well sample concentration and then normalizes the raw data to show RFU values. Wells are selectively reread at the optimal PMT setting. Photo-bleaching is eliminated because wells are not read unnecessarily. Must incorporate the patented PathCheck sensor (U.S. Patent 5,959,738) - the only sensor of its kind not affected by temperature, and requires no accessories to measure the pathlength of the sample in all individual microplate wells. The pathlength measurement can be used to calculate concentrations without a standard curve, test liquid handling devices, detect and correct for pipetting errors, and expand the dynamic range of the assay. Must have the option to run the reader with a slow carriage speed to increase assay precision. Must have the following read times (minutes:seconds): 96-well 384-well • Absorbance 0:18 0:49 • Fluorescence Intensity 0:15 0:45 Must have thermal regulation for temperature dependent kinetic assays. Temperature is regulated up to 45°C. Three heat sources provide uniform temperature regulation across the plate (+/- 0.5°C well-to well @ 37°C). One heat source above the plate creates a small temperature differential eliminating plate lid fogging during kinetic runs. Must offer compliance support tools including: • Software validation package • IQ/OQ/PQ documentation • Physical validation test plates for absorbance and fluorescence Must offer automatic validation of absorbance performance with the SpectraTest TM ABS1 validation plate. The SpectraTest ABS1 validation plate provides NIST traceability, and performs 8 tests to easily verify optical performance for GXP compliance. Must offer automatic validation of fluorescence performance with the SpectraTest TM FL1 validation plate. The SpectraTest FL1 validation plate performs 12 tests to easily verify optical performance for GXP compliance. Must be robot-compatible for automation without requiring any instrument modification. Must ship with software that provides microplate reader data acquisition and analysis support for both Windows XP and Macintosh OS X operating systems. Software must offer a common file format that allows data files to be edited, saved, and shared by users on both Windows XP and Macintosh OS X, provided on one CD-ROM. Software must ship with many read-to-run protocols for a variety of common assay applications. Software must have ability to design custom assay protocols or customize existing protocol to create meaningful reports, graphs, and multi-plate summaries, including data trend analysis. Also must be able to save protocol as a menu-available choice so that one touch of the Read button will allow completion of data report in final format. Software must allow for the ability to auto save multiple copies of assay data in all desired formats: • SoftMax Pro native •.TXT files •.XML files •.PDF Files (Mac OS X) Software must allow the following data analysis tools: • Simultaneous evaluation of multiple standard curves • Ability to easily graph multiple plots on multiple graph sections • 4- and 5-parameter curve fitting with parallel line analysis • BOOLEAN operators If, And, Or, Not, False, True • Auto-repair of broken formula links Software must support regulatory compliance requirements such as FDA 21CFR part 11, GLP, GMP, etc (collectively referred to as GXP). Software must have control over virtually every aspect of the microplate reader solution to meet these "GXP" regulations. These controls include required user logon, management of guest access, granular permission structure, support for electronic signatures, operation of reader within permissions structure, complete experiment audit trails, network and local AutoSave. Interested sources that are capable of providing the equivalent supply listed above are encouraged to submit statements of capability to the contracting office. Small Business concerns are encouraged to participate. This is not a request for competitive proposals Information received will be considered solely for the purpose of determining whether to possibly conduct a competitive procurement in the future. No requests for capability briefings will be honored as a result of this notice. Interested sources who submit data are responsible for appropriately marking information if it is proprietary in nature. Please provide Tax I.D. Number, Duns Number, point of contact information, past performance and references regarding your ability to provide this item and or service along with your Statement of Capability. The Government will not award a contract based on the information received, nor reimburse participants for information they provide. Information provided is strictly voluntary. Please fax Statements of Capability to Carol Dingess at 612-336-3550 or email to Carol.Dingess@aphis.usda.gov. Email is the preferred method of communication. Telephonic inquiries will not be honored. Closing date for submissions of Statement's of Capability is August 03, 2009 at 4:00PM ET. The North American Industry Classification Code (NAICS) is 334516 with a small business size standard of less than 500 employees
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/USDA/OPPM/POD/299143/listing.html)
- Place of Performance
- Address: USDA/APHIS/VS/NVSL/6197, 1800 DAYTON ROAD, AMES, Iowa, 50010, United States
- Zip Code: 50010
- Zip Code: 50010
- Record
- SN01884351-W 20090724/090723000434-8a26a615c13912b30f1dcb870476f40d (fbodaily.com)
- Source
-
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