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FBO DAILY ISSUE OF JULY 16, 2009 FBO #2789
SOLICITATION NOTICE

99 -- Schrodinger Molecular Modeling Software and Support

Notice Date

7/14/2009
 

Notice Type

Combined Synopsis/Solicitation
 

NAICS

511210 — Software Publishers
 

Contracting Office

Department of Health and Human Services, National Institutes of Health, National Library of Medicine, 6707 Democracy Blvd., Suite 105, Bethesda, Maryland, 20894, United States
 

ZIP Code

20894
 

Solicitation Number

NLM-09-139jc
 

Archive Date

8/7/2009
 

Point of Contact

Joan Coulter, Phone: 301-496-6546
 

E-Mail Address

coulterj@mail.nih.gov
(coulterj@mail.nih.gov)
 

Small Business Set-Aside

N/A
 

Description

This is a combined synopsis/solicitation for Commercial Items prepared in accordance with the format in Federal Acquisition Regulation (FAR) Subpart 13.5, Test Program for Certain Commercial Items, as supplemented with additional information included in this announcement. This solicitation incorporates provisions and clauses in effect in the March 2005 FAR Revision, including all FAR Circulars issued as of the date of this synopsis. It is the intent of the Center for Information Technology (CIT), National Institutes of Health (NIH), to negotiate on a sole source basis with Schrodinger LLC, 101 SW Main Street, Suite 1300, Portland, Oregon 97204, to renew NIH-wide licenses for a group of Schrodinger proprietary molecular modeling software products and support. CIT has acquired annual licenses to Schrodinger molecular modeling software products on a sole-source basis since 2000 which currently consist of interchangeable tokens (i.e., "floating licenses") that allow NIH researchers to concurrently run the various Schrodinger molecular modeling software products as required. Renewal of the Schrodinger software licenses are required by the Center for Molecular Modeling (CMM), Division of Computational Bioscience, CIT. CMM is a major supplier of molecular resources and expertise to the NIH research community, organizes molecular modeling users at the NIH by sponsoring the NIH inter-institute Molecular Modeling Interest Group, and created a distributed molecular modeling environment that is accessible from UNIX workstations and personal computers maintained by individual NIH investigators. CMM's computational chemists collaborate with NIH researchers on molecular modeling-related projects by providing expertise on scientific interests that include modeling of macromolecular structure and dynamics, structure-function relationships of macromolecules, macromolecular interactions, and ligand binding. In order to continue providing expert support to the NIH research community, CMM requires the continued use of commercially available molecular modeling software products for the 12-month period of 08-01-09 through 07-31-10 that provide all of the following functionalities: (1) a powerful and innovative software application for accurate protein structure predictions; (2) a fully-integrated protein structure program that provides an easy-to-use interface that takes a novice user intuitively from sequence to alignment to refined structure; (3) the ability to provide the expert user complete control over calculational settings to maximize accuracy of predictions; (4) a powerful and complete tool for generating accurate receptor models for structure-based drug design; (5) the ability to combine leading force fields, accurate effective solvation models, and advanced conformational searching methods that provide the most complete molecular modeling package suitable for a wide array of research; (6) a complete solution for ligand-receptor docking which provides the full spectrum of speed and accuracy from high-throughput virtual screening of millions of compounds to extremely accurate binding mode predictions with consistently high enrichment at every level; and (7) the ability of the software products to work with each other to simulate receptor flexibility in response to ligand-binding events. After consulting with NIH researchers, particularly from the National Cancer Institute (NCI) and the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), CIT has determined that the Schrodinger software products are the only commercially available ones that can provide the required combination of comprehensive molecular modeling functionalities described above that are required by NIH researchers. This notice of intent is not a Request for Quotations (RFQ), nor is an RFQ available. However, all responsible and responsive sources may submit descriptive literature fully documenting their molecular modeling software applications and support which will be considered by the agency. Sources interested in responding to this notice must be able to provide software and support that can fulfill all of the requirements specified above. Information received in a timely manner will be considered solely for the purpose of determining whether to conduct a competitive procurement. A determination by the Government to conduct a competition for this proposed acquisition based upon responses to this notice is solely within the discretion of the Government. This requirement is being processed for CIT by the National Library of Medicine (NLM). NLM intends to make an award for these commercial items in accordance with FAR Subpart 13.5, Test Program for Certain Commercial Items. The following clauses and provisions apply to this acquisition and may be obtained from the web site http://rcb.cancer.gov/rcb-internet/SAP/sap.htm: FAR 52.212-1, Instructions to Offerors; 52.212-3, Offeror's Representations and Certifications; 52.212-4, Contract Terms and Conditions, and FAR 52.212-5, Contract Terms and Conditions Required to Implement Statutes. The contractor shall comply with all other applicable Federal, state, and local laws, executive orders, rules and regulations in effect at time of award. Full text of FAR clauses and provisions are available at: http://www.arnet.gov/far/index.html. Responses must be received by the NLM Point of Contact within seventeen (17) calendar days from the publication date of this notice. NLM Synopsis No. NLM-09-139-JC shall be noted on all correspondence to this announcement. RESPONSES SHALL BE SENT VIA EMAIL TO: Joan Coulter, Business Opportunity Specialist at jc224a@nih.gov. Inquiries regarding this notice may be made to Joan Coulter (301) 496-6546; Fax 301 402-0642.
 

Web Link

FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/NIH/OAM/NLM-09-139jc/listing.html)
 

Place of Performance

Address: National Library of Medicine, Two Democracy, Room 105, 6707 Democracy Boulevard, MSC 5488, Bethesda, Maryland, 20892-5488, United States

Zip Code: 20892-5488
 

Record

SN01875212-W 20090716/090715000825-60f926365edd742f27718d356c2864df (fbodaily.com)
 

Source

FedBizOpps Link to This Notice
(may not be valid after Archive Date)

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