SOLICITATION NOTICE
A -- Pathology Monitoring of Aged Rodent Colonies
- Notice Date
- 6/10/2009
- Notice Type
- Presolicitation
- NAICS
- 541940
— Veterinary Services
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Institute on Mental Health, Contracts Management Branch, 6001 Executive Blvd, Rm 8154, MSC 9661, Bethesda, Maryland, 20892-9661
- ZIP Code
- 20892-9661
- Solicitation Number
- HHS-NIH-NIDA(AG)-RFP-09-059
- Archive Date
- 5/1/2010
- Point of Contact
- Rosanne S Wilson, Phone: 301-443-4433, Teresa A. Baughman, Phone: (301) 443-1193
- E-Mail Address
-
wilsonr@mail.nih.gov, baughmat@nida.nih.gov
(wilsonr@mail.nih.gov, baughmat@nida.nih.gov)
- Small Business Set-Aside
- N/A
- Description
- The National Institute on Aging (NIA), National Institutes of Health (NIH), Department of Health and Human Services (DHHS) intends to recompete a requirement currently being performed by BioReliance under NIA Contract HHSN260200500003C (N01AG50003). This procurement is being competed under full and open competitive procedures under NAICS 541940. It is anticipated that Part 12, Acquisition of Commercial Items will be used and a single firm fixed price type contract will be awarded for a 5-year period of performance beginning on or about March 1, 2010. Biomedical research is supported by the National Institutes of Health (NIH), National Institute on Aging (NIA) through several programs which require animals as models of the aging process. To facilitate this research, the NIA has established contracts for the supply of genetically defined, barrier-reared aged rats and mice to be made available to investigators for aging research. The National Institute on Aging (NIA) is planning to procure services for Pathology Monitoring of Aged Rodent Colonies. The purpose of this contract is to provide independent surveillance of the health status of National Institute on Aging (NIA)-supported, contractor-maintained colonies of aged rats and mice. The aim is to provide confirmation of results reported by the colony contractor, to serve as a research resource for resolution of questions on animal health, and to provide advice on animal health management practices. The objective of this project is to provide an independent surveillance of the health status of rodents maintained in contractor facilities for the aged rodent colonies. The evaluation to be performed will include gross pathology, histopathology, microbiology, parasitology and serology. There are four colonies to be covered by this contract: the Fisher 344 rat colony; the multi-genotypic mouse colony; the caloric-restricted colony (rat and mouse); and the hybrid rat colony. The Contractor shall perform clinical evaluation of mice and rats selected by the Project Officer from the NIA colonies and shipped at no cost to the contractor. Total numbers of mice and rats to be evaluated will range between 520 and 900 per year. No more than 30 animals will be shipped in any one week. As part of the assessment, the contractor shall describe general conditions of all animals, weight, and any visible lesions or symptoms, conduct a gross pathology examination on all animals, and evaluate eighty percent (80%) of the animals with the Basic Profile (below) and the other twenty percent (20%) with the Comprehensive Profile, which includes the Basic Profile plus additional tests listed under Comprehensive Profile. All tests are applied to both rats and mice unless indicated specific to either rats (R) or mice (M). Basic Profile: Serology- MHV (M), Ectromelia virus (M), Mouse parvovirus(es) (M), Theiler's (M), PVM, LCMV (M), Rotavirus (M), Sendai, Rat Parvoviruses (R), and Rat coronovirus (R); Microbiology - Mycoplasma pulmonis, Corynebacterium kutscheri, Streptococcus pneumoniae, Citrobacter freundii (4280), Pseudomonas sp., and Salmonella enteritidis; Parasitology- Spironucleus muris, Giardia sp., Cryptosporidium sp., Syphacia sp., Hymenolepis sp., and Mites; Histopathology - GI tract: Small intestine, Cecum, and Colon, Respiratory tract: Nasal passages, Middle ears, Lungs, Trachea, and Liver. Comprehensive Profile: Serology - Reovirus(es), Polyomavirus (M), Adenoviruses, LDV (M), TMEV (R), Hantavirus (R); Microbiology- CAR bacillus (histopathology), Pasteurella pneumotropica, Bacillus piliformis (histopathology), and Helicobacter; Histology - Spleen, Thymus, Heart, Kidney, Reproductive organs: Ovaries, Uterus, Testes, and Prepuce, Brain, Skin, Salivary gland, and Harderian gland. Excess tissue can be disposed of upon completion of the analysis. Slides and embedded tissue blocks are to be archived for a period of 1 year, after which they may be discarded unless otherwise specified by the Project Officer. The Contractor must be prepared to accept delivery of archived slides and tissue blocks from the previous contract and store them for the remainder of the one year archival period. REPORTS/DELIVERABLES: (1) Pathology reports - The data generated from these evaluations will be gross pathology, histopathology, microbiology, parasitology, and serology data on each individual animal submitted for evaluation. (2) Annual report - This report shall consist of a summary of the number of animals evaluated and a Contractor's statement regarding the significance of these results in terms of the success of colony management practices and the health of colony animals. (3) Final report - The Contractor shall submit, with the final report, a summary of salient results achieved during the performance of the contract. All responsible sources may submit a proposal which will be considered by the agency. This notice does not commit the Government to award a contract. No collect calls will be accepted. No facsimile transmissions will be accepted.
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/NIH/NIMH/HHS-NIH-NIDA(AG)-RFP-09-059/listing.html)
- Record
- SN01840960-W 20090612/090610235056-27983b4986686145e7d2e4743ca38d4b (fbodaily.com)
- Source
-
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