SOURCES SOUGHT
A -- Human Genetics Resource Center
- Notice Date
- 6/13/2007
- Notice Type
- Sources Sought
- NAICS
- 541710
— Research and Development in the Physical, Engineering, and Life Sciences
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Institute of Neurological Disorders and Stroke, 6001 Executive Boulevard, Neuroscience Center, Suite 3287, MSC 9531, Bethesda, MD, 20892-9531, UNITED STATES
- ZIP Code
- 00000
- Solicitation Number
- Reference-Number-SS-NS-07-11
- Response Due
- 6/29/2007
- Archive Date
- 7/14/2007
- Description
- The National Institute of Neurological Disorders and Stroke (NINDS) is interested in identifying Small Business organizations with requisite qualifications to maintain and further develop a repository for the receipt and distribution of blood samples, DNA, cell lines, and associated phenotypic and genotypic data. The NINDS is seeking Small Business Capability Statements at this time in order to determine if this future requirement can be set-aside exclusively for small business concerns. THIS ANNOUNCEMENT IS NOT A REQUEST FOR PROPOSALS, and if your business concern is NOT a small business, there is no need to respond to this announcement. Once a determination is made regarding the suitability of this future requirement for a small business set-aside (or an open competition to include both large and small businesses), a separate Pre-Solicitation Announcement would be issued in advance of the release of a Request for Proposals. The applicable North American Industry Classification System (NAICS) code for this requirement is 541711. Therefore, the small business size standard for this announcement is 500 or fewer employees. Please note that in order to qualify as an eligible small business for purposes of a small business set-aside (where large businesses would be excluded from competing), at least 50% of the direct labor cost must be ?in-house?. Specifically, FAR 52.219-14, ?Limitations on Subcontracting,? states that ?at least 50 percent of the cost of contract performance incurred for personnel shall be expended for employees of the concern.? Submitted Capability Statements must address how the business meets the applicable size standard. The National Institute of Neurological Disorders and Stroke (NINDS) has the stated mission to reduce the burden of neurological disease?a burden borne by every age group, by every segment of society, by people all over the world. Within this mission falls gene discovery. Gene discovery elucidates the cause of some diseases, and also, the underlying pathogenesis of related disorders. Therefore, this contract re-competition, which will build an infrastructure to support and encourage gene discovery, serves the mission of NINDS. Such studies require a large and diverse sample and accompanying information base. Thus, a repository of DNA samples, immortalized cell lines (from which DNA can be extracted continuously), and accompanying clinical and pedigree data is clearly an invaluable resource for the neuroscience community. The NINDS repository, established in 2002, receives, stores, and distributes DNA, Cell lines, and accompanying clinical and genotypic data to the Neuroscience community. It will ensure that research participants will be making a maximal contribution, and decrease duplicative sampling efforts. It allows collection of a sample set that is large enough to discover common genetic risk factors for neurological disorders. It will also ensure that a standardized, useful dataset of demographic, other phenotypic, and genotypic data is managed and curated to allow sharing publicly via NLM?s DbGaP. The objective of this requirement is to continue the growth of the sample numbers and types, the data complexity, the administrative role and the data management capabilities of the NINDS DNA sample and cell line repository for human gene discovery. To be deemed capable, a small business must demonstrate their ability and related experience in a requirement-specific Capability Statement to: 1) Receive, process, store, and distribute Whole blood, and buccal swabs from individuals with neurological disorders as well as from healthy individuals into cell lines and DNA; 2) Manage and track administrative study documents, phenotypic and genotypic data; 3) monitor human subject concerns compliance with federal and other human subject regulations, to include a means of masking individual identities to ensure confidentiality; 4) Maintain flexibility in order to expand as needed to accomplish aims of related or overlapping projects; 5) Provide rapidly, upon request, as well as routinely, cell lines and DNA samples to submitters and sample withdrawers as well as associated data using a fee based system to offset costs; 6) transfer the existing NINDS repository of DNA and cell lines as well as data to their organization to allow seamless functioning of the existing project; 7) have the capacity to store, distribute, and process the current collection of over 16 thousand samples plus an additional 10 thousand biological samples and associated complex phenotypic data; 8) to develop, a website as well as transfer the existing web-based system and maintain and modify it based on needs of the resource and 9) develop, transfer, and maintain a database of all associated data and resources needed to manage the data and user interface for the project. Small Businesses that meet the applicable size standard and believe that they have the capabilities described above are encouraged to submit 3 copies of your written Capability Statement to the attention of Jason Williams, Contracting Officer at the address provided by 3:00 PM Local Time on Friday, June 29, 2007. Capability Statements should be limited to no more than 15 pages and should specifically address each of the competencies stated above. A generic marketing brochure would not suffice for purposes of determining a small business to be capable for this requirement. If responses indicate a reasonable expectation of obtaining competitive offers from two or more responsible and capable small business concerns, the anticipated subsequent Request for Proposals will be set-aside for small businesses only and a future Pre-Solicitation Notice for this requirement would indicate this determination. This Small Business Sources Sought Announcement is for information and planning purposes only and shall not be construed as a solicitation or as an obligation on the part of the Government. The Government does not intend to award a contract on the basis of responses nor otherwise pay for the preparation of any information submitted or the Government?s use of such information. Acknowledgment of receipt of responses will not be made, nor will respondents be notified of the Government?s evaluation of the information received. However, should such a requirement materialize, no basis for claims against the Government shall arise as a result of a response to this Small Business Sources Sought announcement or the Government?s use of such information as either part of our evaluation process or in developing specifications for any subsequent requirement. Responses will be held in a confidential manner. Any proprietary information should be so marked. Please submit 3 copies of your Capability Statement to: Jason Williams, Contracting Officer, National Institutes of Health, NINDS Contracts Management Branch, 6001 Executive Blvd., Suite 3287, Rockville, MD 20852. Electronic submittal will also be accepted at willjas@mail.nih.gov (please format for printing).
- Record
- SN01317533-W 20070615/070613220651 (fbodaily.com)
- Source
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