SOLICITATION NOTICE
70 -- Genedata Screener Software
- Notice Date
- 3/15/2007
- Notice Type
- Solicitation Notice
- Contracting Office
- Environmental Protection Agency, Ord Service Center/Nerl, Rtp Procurement Operations Division, Research Triangle Park, NC 27711
- ZIP Code
- 27711
- Solicitation Number
- RFQ-RT-07-00103
- Response Due
- 3/22/2007
- Archive Date
- 4/22/2007
- Description
- NAICS Code: 541511 The U.S. Environmental Protection Agency (EPA) intends to negotiate a sole source purchase order under Simplified Acquisition Procedures to Genedata, Inc. 1601 Trapelo Rd, suite 350, Waltham, MA 02451, for the acquisition of a one year license for Genedata Screener software. The National Center for Computational Toxicology (NCCT)is embarking on a new program, ToxCast, which requires the collection and management of large volumes of high-throughput screening (HTS) data. Current plans include testing chemicals in batches ranging into the thousands through assays numbering in the hundreds. Each of these tests, i.e. one chemical in one assay, will produce data needing curating, storage and analysis. Scientists traditionally relied on spreadsheet programs to manage assay results. However, this is completely impractical for the amount of data generated through HTS approaches. NCCT requires a database and tools that must have the following capabilities: (1) Flexibility in building templates for calculation of raw plate-based data; (2) Visualization of plate-based data for QC analysis; (3) Robust concentration-response curve fitting routine;(4) Ability to link chemicals in sample plates to assay results; (5) Operational database supporting mass storage of data and analysis results. A large amount of data for ToxCast will be generated at the National Institutes of Health, Chemical Genomics Center (NCGC). Their unique approach to HTS, termed quantitative HTS (qHTS), tests all chemical in concentration-response format. This presents unique challenges in dat QC and management. Curve fitting routines must be extremely robust to routinely and efficiently handle thousands of test results. This is an absolutely critical step in the analysis of collaboration with NCGC. In addition, other products have laborious procedures required to build specific templates for calculating raw data for HTS assays. Because ToxCast will be acquiring data from a number of different sources and for a large number of different assays (hundreds), the ability to easily build templates for data calculation sophisticated visualization of plate-based data, an interface to link sample information with assay results, and an operational database sufficient to meet the long-term requirements of the ToxCast Program. The EPA has identified Genedata, Inc., the only vendor capable of satisfy the requirement. In order to ensure data compatibility and accuracy The circumstance permitting "other than full and open competition" is FAR 13.106(B)"Only one source reasonably available". The intent of this notice is to determine if any other source(s) exist, and therefore, no solicitation (RFQ) is available. Consequently, any response failing to provided the aforementioned data and instead choosing to merely submit a routine letter requesting a copy of the RFQ will be ignored. Interested parties who can meet the above requirements may submit written qualification statements, fully explaining their capability no later than 10 days after the date of this publication. Submit response to the U.S. EPA, Attn: Pamela E. Smith (MC-E105-02), RTP Procurement Operations Division, Research Triangle Park, NC 27711. No telephonic or faxed request will be honored.
- Record
- SN01252333-W 20070317/070315222749 (fbodaily.com)
- Source
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