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FBO DAILY ISSUE OF JUNE 08, 2005 FBO #1290
SOLICITATION NOTICE

66 -- Axon Genepix 4000B Microarray Scanner

Notice Date
5/4/2005
 
Notice Type
Solicitation Notice
 
NAICS
334516 — Analytical Laboratory Instrument Manufacturing
 
Contracting Office
Department of Health and Human Services, National Institutes of Health, National Cancer Institute, Research Contracts Br., 6120 Executive Blvd. EPS Suite 600, Rockville, MD, 20852
 
ZIP Code
20852
 
Solicitation Number
RFQ-NCI-50042-01
 
Response Due
5/19/2005
 
Point of Contact
Malinda Holdcraft, Purchasing Agent, Phone (301) 402-4509, Fax (301) 402-4513, - Renita Smith, Contract Specialist, Phone 301-496-8612, Fax 301-480-0241,
 
E-Mail Address
holdcram@exchange.nih.gov, rs442i@nih.gov
 
Description
The National Cancer Institute (NCI), Center for Cancer Research (CCR), plans to procure on a sole source basis for the brand name Axon Genepix 4000B Microarray Scanner as authorized in FAR Part 13.1. This acquisition will be conducted in accordance with the simplified procedures provided in FAR 13. The North American Industry Classification System code is 334516 and the business size standard is 500 employees. The following salient characteristics apply: 1) Ability to scan standard microscope slides bearing in-house printed microarrays or commercial microarrays from NimbleGen Biosystems, with non-confocal technology, 2) Ability to accurately and reproducibly scan at 10 micro or 5 micro resolution, to accommodate the above mentioned arrays’ format, 3) ability to scan two channels (laser excitation wavelengths of 532 and 635 nm), 4) High dynamic range of detection, 5) ability to acquire and save single or double-wavelength images of the array for analysis on NCI web-based software, 6) Must fit in a small footprint, not to exceed 16" Wide, 24" Long and 24" High, 7) Must come with software to run scanner, 8) Scanner software must enable on-the-fly feature visualization and histogram generation, for PMT optimization during scanning, and an option for automated PMT gain setting, 9) Machine software must be able to export color images in 24-bit JPEG format for analysis on NCI web-based software, 10) Microarray analysis software must be able to recognize features that are circular, square or irregular, with some flexibility for imperfect spotting, and to align the spots in terms of row, column and block, 11) Software must be able to import GAL files that identify the genes represented in all features, 12) Microarray analysis software must have user-defined manual as well as automatic flagging features for quality control and normalization and, 13) Microarray analysis software must have ability to visualize background pixels and to perform multiple methods of background subtraction. Justification: The Axon Genepix 4000B microarray scanner is required for the use of the NimbleGen arrays, which are being used in current studies, are very specialized in that the size of the oligonucleotide features (5 microns) on their microarrays is so small that only certain scanners have the resolution to allow acceptable imaging and quantification of the signals produced. The Axon Genepix 4000B microarray scanner is the most compatible scanner in using the NimbleGen microarrays. The existing scanner that NimbleGen scientists are currently using in their in-house microarray service core is the Axon Genepix 4000B. Changing the scanner for future microarrays will change the variables and will interrupt correct interpretation of the studies being currently performed. Potential Offerors may request a copy of the solicitation from Malinda Holdcraft via electronic mail at holdcram@exchange.nih.gov or via fax on (301) 402-4513. If you have questions regarding this notice, they may be addressed to Malinda Holdcraft via electronic mail or telephone. Estimated issue date of the solicitation is May 19, 2005 with an estimated due date of May 26, 2005. No collect calls will be accepted. Please reference the RFQ-NCI-50042-NG-01, on your written request. In order to receive an award Contractor must be registered in the Central Contractor Registration (CCR) www.ccr.gov, and the Online Representations and Certifications Applications, (ORCA) at http://orca.bpn.gov. NOTE: THIS NOTICE MAY HAVE POSTED ON WWW.FEDBIZOPPS.GOV ON THE DATE INDICATED IN THE NOTICE ITSELF (04-MAY-2005). IT ACTUALLY APPEARED OR REAPPEARED ON THE FEDBIZOPPS SYSTEM ON 06-JUN-2005, BUT REAPPEARED IN THE FTP FEED FOR THIS POSTING DATE. PLEASE CONTACT fbo.support@gsa.gov REGARDING THIS ISSUE.
 
Web Link
Link to FedBizOpps document.
(http://www.eps.gov/spg/HHS/NIH/RCB/RFQ-NCI-50042-01/listing.html)
 
Place of Performance
Address: NIH/NCI Bethesda, MD
Zip Code: 20892
Country: USA
 
Record
SN00823787-F 20050608/050606212723 (fbodaily.com)
 
Source
FedBizOpps.gov Link to This Notice
(may not be valid after Archive Date)

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