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FBO DAILY ISSUE OF APRIL 16, 2005 FBO #1237
SOURCES SOUGHT

R -- Yeast Two-Hybrid Screening

Notice Date
4/13/2005
 
Notice Type
Sources Sought
 
NAICS
541990 — All Other Professional, Scientific, and Technical Services
 
Contracting Office
Department of Health and Human Services, National Institutes of Health, National Institute of Allergy & Infectious Diseases/AMOB, 10401 Fernwood Drive, Suite 2NE70, MSC 4811, Bethesda, MD, 20817
 
ZIP Code
20817
 
Solicitation Number
NIAID-DIR-05-42
 
Response Due
3/23/2005
 
Point of Contact
Terrie Nestor, Contract Specialist, Phone 301-402-6790, Fax 301-480-0689,
 
E-Mail Address
tnestor@niaid.nih.gov
 
Description
The National Institute of Allergy and Infectious Diseases (NIAID), Acquisitions Management and Operations Branch (AMOB) is seeking sources that can provide yeast two-hybrid analysis of proteins. Offerors must be capable of analyzing each protein as multiple overlapping fragments engineered as DNA-binding domain constructs (DBD Constructs); preparing custom activation domain libraries; generating and screening each of the DBD Constructs against up to three different activation domain libraries; reproducing all interactions in na?ve yeast and confirming specificity using multiple microbial DBD Construct controls; providing continuous access to the protein interaction data via a secure, web-based interface; and providing access to a curated database of publicly reported protein-protein interactions. Offerors must have significant operational experience utilizing yeast two hybrid screening technology to detect host-pathogen protein-protein interactions. NIAID intends to award a one year contract beginning on or about May 1, 2005 with the option for four additional contract years. This is not a request for proposals. The intention of this announcement is to survey the market for potential offerors. Potential offerors must provide a capability statement to Terrie Nestor at tnestor@niaid.nih.gov on or before March 17, 2005 at 2:00pm. Capability statements must indicate the business size of the company. NOTE: THIS NOTICE WAS NOT POSTED TO WWW.FEDBIZOPPS.GOV ON THE DATE INDICATED IN THE NOTICE ITSELF (13-APR-2005). IT ACTUALLY APPEARED OR REAPPEARED ON THE FEDBIZOPPS SYSTEM ON 14-APR-2005. PLEASE CONTACT fbo.support@gsa.gov REGARDING THIS ISSUE.
 
Place of Performance
Address: N/A
 
Record
SN00788529-W 20050416/050414212902 (fbodaily.com)
 
Source
FedBizOpps.gov Link to This Notice
(may not be valid after Archive Date)

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