SOLICITATION NOTICE
B -- LABORATORY SUPPORT FOR PROCESSING AND STORAGE OF BIOLOGICAL SPECIMENS FROM PERSONS AT HIGH RISK OF CANCER
- Notice Date
- 2/15/2005
- Notice Type
- Solicitation Notice
- NAICS
- 541710
— Research and Development in the Physical, Engineering, and Life Sciences
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Cancer Institute, Research Contracts Br., 6120 Executive Blvd. EPS Suite 600, Rockville, MD, 20852
- ZIP Code
- 20852
- Solicitation Number
- N02-CP-51011-66
- Response Due
- 4/6/2005
- Archive Date
- 10/14/2005
- Description
- LABORATORY SUPPORT FOR PROCESSING AND STORAGE OF BIOLOGICAL SPECIMENS FROM PERSONS AT HIGH RISK OF CANCER. The Office of the Director (OD), Division of Cancer Epidemiology and Genetics (DCEG), National Cancer Institute is seeking a contractor to provide for the maintenance of the existing inventory of biologic specimens and to receive, process and store new samples as they are collected. The Contractor will provide services in accordance with Contractor developed, Government approved protocols for: a) Separation and viable cryopreservation of blood mononuclear lymphocytes; b) Separation, aliquoting and storage of serum, plasma and/or urine as needed; c) Cryopreservation of bone marrow samples; d) Cryopreservation of whole tumor tissue; e) Viable cryopreservation of previously established lymphoblastoid cell lines; f) Storage of DNA and other biological materials as specified by the Project Officer (e.g., pathology slides and tissue block); g) Extraction of DNA from biologic materials; h) Specimen processing as required by NCI to preserve special biologic materials; i) Logging in, labeling and tracking of each vial of each sample employing an NCI developed computerized specimen tracking system, including all laboratory safeguards to insure the fidelity and purity of each sample; j) Maintenance of the previously-established repository currently containing more than 2.9 million biological specimens and allowance for an estimated increase of up to 50% of freezer storage space; k) Under the direction of the Project Officer conduct laboratory methods studies that establish optimal conditions for collection, processing, shipping and storage of biologic materials. The current repository contains approximately 100 mechanical ?80oC freezers, 41 liquid nitrogen freezers, 1 -20oC upright freezer, 1 walk-in ?20oC freezer, 1 walk-in +4oC refrigerator, 3 12-drawer slide cabinets, and 1 storage unit for flammable materials. In order to prepare for the storage of additional specimens expected to arrive in the repository during the next contract, an additional 21 liquid nitrogen freezers, 28 mechanical freezers, 1 walk-in refrigerator and 1 walk-in -20oC freezers are being ordered. Processing services shall be available routinely between the hours of 9:00 a.m. and 2:00 p.m., Monday through Friday, and at any other time (including nights, weekends and holidays) by special arrangement, usually with advance notice. A laboratory staff member shall be available during non-?business hours for emergency specimen processing (as might occur when a patient dies). A biohazard area adequate for processing specimens with Acquired Immunodeficiency Syndrome (AIDS) shall be available for the processing of all biologic samples. The Contractor shall be prepared to process the following quantities of materials: Material type or task Max Daily Typical total monthly volume (vials) (vials) 1) Fresh blood, mouthwash (buccal cells) , urine for immediate processing 30 700 2) Process whole blood to lymphocyotes and cryopreserve (included in #1) 10 250 3) EBV transformation of lymphocytes or whole blood (included in #1) na 10 4) Withdrawing vials from inventory 700 15,000 5) Adding vials to inventory 1,000 22,000 6) Thawing/aliquoting miscellaneous specimens including DNA na 2,000 7) DNA purification na 2,000 The Government envisions a staff composed of the following: 18 FTEs: 1) Principal Investigator 0.25 FTE; 2) Professional Staff 2.0 FTE; 3) Lab Technicians 12 FTE; 4) Data entry/admin 3 FTE; and 5) Driver 0.75 FTE. The contractor must be within 1 hour driving time to 6120 Executive Blvd., Rockville, MD. Award is anticipated by October 2005. The contractor is expected to provide the facilities and all major equipment. Additional Government furnished equipment currently in use under the existing contract will be provided. It is anticipated that the RFP will be available on/about March 3, 2005 with responses due within 30 calendar days after the actual date of issuance of the solicitation. All responsible sources may submit a proposal which shall be considered by the NCI. No collect calls will be accepted.
- Record
- SN00751137-W 20050217/050215211719 (fbodaily.com)
- Source
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