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A -- Knockout Mice and Database

Notice Date
Notice Type
541710 — Research and Development in the Physical, Engineering, and Life Sciences
Contracting Office
Department of Health and Human Services, National Institutes of Health, National Institute of Environmental Health Sciences, Research Contracts Branch, DERT P.O. Box 12874, 79 T.W. Alexander Dr, Bldg 4401, RTP, NC, 27709
ZIP Code
Solicitation Number
Response Due
Archive Date
Point of Contact
Tommy Hardee, Contract Officer, Phone 919-541-0429, Fax 919-541-2712, - PHIL JONES, Supervisory Contracting Officer, Phone 919-541-0426, Fax 919-541-2712,
E-Mail Address
hardee@niehs.nih.gov, jonesp@niehs.nih.gov
The purpose of this modification to synopsis is to alert interested parties of the Government?s decision to open the acquisition to full and open competition. This announcement also introduces resultant clarifications to the original announcement, repeated here for convenient reference. The National Institute of Environmental Health Sciences intends to solicit proposals on a competitive basis for the acquisition of an irrevocable, perpetual license to use 750 knockout mice, delivered as frozen embryos, sperm, and ES cells to designated Depositories, which shall act under separate contract to NIH to maintain and distribute the material. All these mice should carry a null allele with a reporter gene. The Depositories will distribute the Materials to academic users along with a royalty-free, fully paid-up, irrevocable, perpetual license to use the Material for non-commercial research purposes. Academic Institutions will be free to file patents on discoveries made with the Material without reach-through rights to the successful offeror or any other party. The Government also intends to acquire a non-exclusive, perpetual, irrevocable, worldwide, fully paid-up license to use and host a database containing detailed phenotyping information on all 750 mice for academic and other non-commercial purposes. Restrictions on the use of the Database for academic and other non-commercial purposes will be removed after four years. The proposed acquisition will include a non-exclusive, perpetual, irrevocable, worldwide, and fully-paid up license to publish in other works or media any of the data from the Database and to create derivative works of any of the data by extracting or reformatting all or any portion of the data, whether in its original form or any revised, annotated or modified forms. The proposed contract will provide to academic investigators world-wide access to a significant fraction of this unique line of knockout mice along with a database containing extensive phenotypic data on each of the 750 knockout lines. The estimated release date for the solicitation is late August. The estimated receipt date for proposals is mid September. Electronic versions of the RFP will be available at http://www.niehs.nih.gov/dert/rtb/rfp.htm. All eligible responsible sources may submit a proposal which shall be considered. See note No. 26.
SN00642301-W 20040814/040812211824 (fbodaily.com)
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