Loren Data's SAM Daily™

FBO DAILY ISSUE OF MAY 22, 2004 FBO #0908
MODIFICATION

66 -- High Throughput Metaphase Finder and Scoring System

Notice Date

5/20/2004
 

Notice Type

Modification
 

NAICS

339111 — Laboratory Apparatus and Furniture Manufacturing
 

Contracting Office

Other Defense Agencies, Uniformed Services University of the Health Sciences, Directorate of Contracting, 4301 Jones Bridge Road, Bethesda, MD, 20814-4799
 

ZIP Code

20814-4799
 

Solicitation Number

HU0001-04-T-1502
 

Response Due

6/7/2004
 

Archive Date

6/4/2005
 

Point of Contact

H. Floyd, Contract Specialist, Phone 301-295-3923, Fax 301-295-1716, - Beverly Roberts, Contracting Officer, Phone 301-295-3868, Fax 301-295-1716,
 

E-Mail Address

hfloyd@uhuhs.mil, broberts@usuhs.mil
 

Description

This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in Subpart 12.6, as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; proposals are being requested and a written solicitation will not be issued. The components described herein depict one congruent system. Offerors must propose systems that meet, or exceed the level of congruency encompassed in the specified system. Only one award will be made as a result of this solicitation. The solicitation document and incorporated provisions and clauses are those in effect through Federal Acquisition Circular 01-23. Delivery shall be made to the following address within 30 days of award: Armed Forces Radiobiology Research Institute (AFFRI) Attn: Dr. Blakely 8901 Wisconsin Ave, Bldg 42 Bethesda, MD 20889-5603 FOB: DESTINATION Clauses incorporated by reference: 52.212-1 -- Instructions to Offerors -- Commercial Items. 52.212-3 -- Offeror Representations and Certifications -- Commercial Items. 52.212-4 -- Contract Terms and Conditions -- Commercial Items. 52.212-5 -- Contract Terms and Conditions Required to Implement Statutes or Executive Orders -- Commercial Items. __X_ 52.222-19, Child Labor--Cooperation with Authorities and Remedies (E.O. 13126). __X_ 52.222-21, Prohibition of Segregated Facilities (Feb 1999) __X_ 52.222-26, Equal Opportunity (E.O. 11246) __X_ 52.222-35, Equal Opportunity for Special Disabled Veterans, Veterans of the Vietnam Era, and Other Eligible Veterans (38 U.S.C. 4212) Note: Each offeror must include a completed copy of the provision at 52.212-3, Offeror Representations and Certifications -- Commercial Items, with its offer. ITEM NO 0001 QUANTITY 2 UNIT Each UNIT PRICE ______________ AUTOMATED SATELLITE WORK STATIONFFPTwo Automated Satellite Chromosome Aberration Analysis Stations along with accessories to work in conjunction with a High Throughput Metaphase Finding and Scoring System for chromosome aberration analysis.The Automated Satellite Chromosome Aberration Analysis Stations work in conjunction with a High throughput Metaphase Finding System to further enhance sample analysis throughput. The microscope stage co-ordinates of automatically searched metaphase spreads using a High Throughput Metaphase Finding System, are digitally transferred to the Automated Satellite Chromosome Aberration Analysis Stations for rapid relocation for analysis by several Technicians. The equipment consists of a satellite work station with a computer, a bionocular high quality research microscope such as Olympus BX41 or equivalent, single slide automated stage with autofocus utility, a firewire camera, and automated bright field scoring and annotating software. Specifications: Automated Satellite Workstation: - 3.2GHz Pentium4 Computer, 512 MbRAM, 120GHD (or above) - 19" FIat LCD Monitor (or above) - DVDRW/CDRWith recorder - High quality binocular research microscope (Olympus BX 41 or equivalent) - 5 Mpixel Color Firewire Camera - Single Slide Automated Stage and Focus - Metaphase Finding and Scoring Software - Automated Satellite Scoring Software for Semi-Automated Scoring and Annotation All Satellites should have the following capabilities: - Semi-Automated Scoring and Annotation for the following assays - Chromosome Aberration Analysis - Sister Chromatid Exchange Analysis - Dicentric Assay Analysis - Mitotic Index Measurements Reviewing and Reporting Software: - Software only review station. - Review High Magnification Photos of each spread - Review Annotation Images - Score from Photos - Generate Reports Automated Metaphase Location Software: - Automated metaphase spread location on samples prepared from human peripheral blood lymphocyte cultures to minimize man-hour requirements for bright field chromosome aberration analysis. - Saves postage stamp image of each spread for rapid user review. - Automatically locates spreads under low power and relocates spreads at high power for user evaluation. - Adaptive Background Correction provides automated adjustment for variation in staining - Preloaded Search Algorithms for different preparations - Spread Location Algorithm - User Modifiable Spread Location Parameters for different preparations - Automated Statistical Analysis and Report Generation - Data Review, Visualization, and Reporting capabilities - GLP Compliance Support - Provides thru-camera light metering for easy setup of microscope illumination - User-Adjustable parameters for spread quality control - Precise scanning and relocation of spreads Semi Automated Scoring and Annotation: - Digital transfer of slide co-ordinates from the High Throughput Metaphase Finder - Ability to "check out" single slide or multiple slides for scoring. - Permanently lock study to prevent further changes to the experiment data for all slides. - System Security limits access to unauthorized users. - Generates summary reports and statistics (chi-square, t-test) for the entire experiment - Automated Statistical Analysis and Report Generation Eliminates transcription errors. - Data Review, Visualization and Reporting - GLP Compliance Support - Semi-Automated Annotation function - Automatically relocates spread on slide for scoring under high magnification. - Should be able to use as an automated one-slide Metaphase Finding System- Metaphase spreads from the most recently reviewed or scanned slide are displayed. - Automatically relocates spread on slide for scoring under high magnification - Photo of metaphase spread at high magnification for later review and documentation - Rapidly enter aberration data using software spreadsheets NET AMT _____________ ITEM NO 0002 QUANTITY 2 UNIT Each UNIT PRICE _____________ REVIEWING AND REPORTING SOFTWARE: - Software only review station. - Review High Magnification Photos of each spread - Review Annotation Images - Score from Photos - Generate Reports Automated Metaphase Location Software: - Automated metaphase spread location on samples prepared from human peripheral blood lymphocyte cultures to minimize man-hour requirements for chromosome aberration analysis. - Saves postage stamp image of each spread for rapid user review. - Automatically locates spreads under low power and relocates spreads at high power for user evaluation. - Adaptive Background Correction provides automated adjustment for variation in staining - Preloaded Search Algorithms for different preparations - Spread Location Algorithm - User Modifiable Spread Location Parameters for different preparations - Automated Statistical Analysis and Report Generation - Data Review, Visualization, and Reporting capabilities - GLP Compliance Support - Provides thru-camera light metering for easy setup of microscope illumination - User-Adjustable parameters for spread quality control - Precise scanning and relocation of spreads Semi Automated Scoring and Annotation: - Digital transfer of slide co-ordinates from the High Throughput Metaphase Finder - Ability to "check out" single slide or multiple slides for scoring. - Permanently lock study to prevent further changes to the experiment data for all slides. - System Security limits access to unauthorized users. - Generates summary reports and statistics (chi-square, t-test) for the entire experiment - Automated Statistical Analysis and Report Generation Eliminates transcription errors. - Data Review, Visualization and Reporting - GLP Compliance Support - Semi-Automated Annotation function - Automatically relocates spread on slide for scoring under high magnification. - Should be able to use as an automated one-slide Metaphase Finding System - Metaphase spreads from the most recently reviewed or scanned slide are displayed. - Automatically relocates spread on slide for scoring under high magnification - Photo of metaphase spread at high magnification for later review and documentation - Rapidly enter aberration data using software spreadsheets NET AMT _____________ ITEM NO 0003 QUANTITY 3 UNIT Each UNIT PRICE ____________ METAPHASE VIBRATION FREE TABLES TECHNICAL SPECIFICATIONS: Isolation Performance @ 5Hz:70-85% @ 10 Hz: 90% Natural Frequency 1.9-2.6 Hz Isolation Method Air suspension Air Supply Requirements Manual Hand Pump Leveling Manual Top Surface Standard FH-Steel laminated with vibration reducing sheet (Specify 'V' after the part number) Brushed Stainless Steel with mounting holes M6 or 1/4-20 (Specify 'FH' plus tap size and spacing i.e. DT-6050 A FH ?-20 x 1) Air Pressure Requirements 3-7 kg/cm2 (20-50psi) Accessories included Hand pump and air valve adjuster SIZES / WEIGHTS Quantity (2) (1) Load Capacity 100 kg 100 kg (221 lb.) (221 lb.) Top Plate Size 600x500 800x600 (23.6x19.6) (31.5x23.6)Overall 692x540x168 892x640x168 (25.7x22.6x3.1) (35.1x25.2x3.1) NET AMT _________________ ITEM NO 0004 QUANTITY 3 UNIT Each UNIT PRICE __________ UNINTERRUPTABLE POWER SUPPLY Minimum Requirements: $150,000 Lifetime Equipment Protection Policy plus a 2-year repair or replace warranty. Product Description: - USB - UPS - 1500 VA - UPS battery - lead acid - Output connector(s) 8 x power NEMA 5-15 - Output Voltage AC 120 V - Input Voltage AC 120 V - Battery Form Factor Plug-in module - Average Run Time 6.7 min at full load - Power Provided 1500 VA - Device Type UPS - Battery UPS battery - lead acid - Warranty 2 years warranty - Form Factor External Ports/Connectors: - Output Connections: (8) NEMA 5-15R outlets - Input Connection Type: NEMA 5-15P - Cord Length: 6 ft. - Communications & Management: (1) DB9 interface port (RS-232) (1) SmartSlot card interface (1) USB port Power Notes: - Output power capacity: 1440VA - Output power capacity: 980 Watts - Max. Configurable Power: 1440VA - Max Configurable Power: 980 Watts - Nominal output voltage: 120V - Waveform Type: Sinewave - Nominal Input Voltage: 120V - Input Frequency: 50/60Hz +/- 3Hz (auto-sensing) - Input Voltage Range for Main Operations: 82 - 144V - Input Voltage Adjustable Range for Main Operations: 75 - 154V Battery Notes: - Typical backup time at half load: 22.8 minutes - Battery type: Maintenance-free sealed Lead-Acid battery with suspended electrolyte (leak-proof) - Typical recharge time: 3 hrs.Surge Protection and Filtering: Surge energy rating: 320 joules - Filtering: Full time multi-pole noise filtering : 0.3% IEEE surge let-through : zero clamping response time : meets UL 1449 NET AMT ________________ ITEM NO 0005 QUANTITY 1 UNIT Each UNIT PRICE __________ METAPHASE FINDER & SCORING SYSTEM Equipment, Accessories, and Supplies: A High Throughput Bright Field Metaphase Finding and Scoring System for chromosome aberration analysis. Summary of Description of the Item: The Highthroughput Metaphase Finding System automatically locates metaphase spreads, obtained from human peripheral blood lymphocyte cultures, on microscope slides under a brightfield microscops and relocates metaphase spreads for user review and aberration analysis. This High Throughput Metaphase Finding System consists of a Pentium Computer (3.2 GHz), a firewire camera, a highquality microscope, an automated stage with autofocus, and slide vacuum delivery robotics. The computer is loaded with a automated metaphase finding software, an interactive automated scoring and annotation software for different types of cytogenetic applications. Specifications: High Throughput Metaphase Finding and Scoring System Hardware: - 3.2GHz Pentium4 Computer, 512 MbRAM, 120GHD - 19" FIatLCD Monitor t. - DVDRW/CDRW recorder - 5 Mpixel Color Firewire Camera - BX41 BrightField Microscope - Single Slide Automated Stage and Focus 150 Slide Vacuum Delivery Robotics Software Applications: - Automated Metaphase Location Software - Semi-Automated Scoring and Annotation - Dicentric Assay Scoring - Chromosome Aberration Scoring - Sister Chromatic Exchange Scoring - Mitotic Index Mpixel Color Firewire Camera Sensor: - Type : 2/3" ICX282AQ progressive scan interline - CCD color (Bayer Mosaic), 5.0 megapixels - Resolution : 2580 x 1944 active pixels - Pixel Size :3.4 um x 3.4 um - Optical Interface : C-mount, 2/3" optical format for microscope or camera lens - Digital Output : 8/10-bit digitization, 30-bit color digitization - Readout Frequency : 20 MHz 8-bit, 10 MHz 10-bit - Frame Rate : 3.5 fps full resolution 8-bit, higher speeds with binning and ROI functions Computerized Control of Camera Function: - Exposure Control : 1.6 milliseconds to 17.9 minutes in 1 microsecond increments - Binning Modes : 2x2, 3x3, and 4x4 with full color images - Shutter Control: Electronic Shutter - ROI: Image size and position control BrightField Microscope Features (Olympus BX41 or equivalent): - Designed for performing in bright field light - Bright 12V/100W halogen light source for transmitted light viewing - Built-in filters (two neutral density and one daylight balancing) for efficient photomicrography - Automated inward-facing five-position nosepiece for easy objective rotation - High-sensitivity fine focusing knob (adjustment gradations: 1 um) - Illuminator Built-in Kohler illumination for transmitted light - Condenser (Numerical aperture 1.1), 4x-100x - 10x, 100x dry plan achromatic objectives - 0.5x C-Mount Adapter Single Slide Automated Stage and Focus: - XY motion: Nanomotors capable of 5 um steps - Focus: Positioning capable of 0.02 um steps - Preloaded search patterns - Focus Algorithms Slide Vacuum Delivery Robotics capable of handling over 100 slides: - Automatically delivers and retrieves sequentially ordered slides for unattended high-throughput microscopic analysis. - Digitally controlled vacuum pick-up unit. - Up to 50 slides are stacked in each storage bin, with a maximum capacity of over 100 slides. - Small laboratory bench top footprint. - Must handle regular 1 "x3" microscope slides, and should be adaptable to larger slide formats (2"x3", 4"x3"). Automated Metaphase Location Software: - Automated metaphase spread location on samples prepared from human peripheral blood lymphocyte cultures to minimize man-hour requirements for chromosome aberration analysis. - Saves postage stamp image of each spread for rapid user review. - Automatically locates spreads under low power and relocates spreads at high power for user evaluation. - Adaptive Background Correction provides automated adjustment for variation in staining - Preloaded Search Algorithms for different preparations - Spread Location Algorithm - User Modifiable Spread Location Parameters for different preparations - Automated Statistical Analysis and Report Generation - Data Review, Visualization, and Reporting capabilities - GLP Compliance Support - Provides thru-camera light metering for easy setup of microscope illumination - User-Adjustable parameters for spread quality control - Precise scanning and relocation of spreads - Semi Automated Scoring and Annotation: - Semi-Automated Scoring and Annotation ability for the following assays - Chromosome Aberration Analysis for genetic toxicology testing of test compounds - Analysis of Sister Chromatic Exchanges - Analysis of radiation induced dicentrics - Measurement of Mitotic Index - Metaphase spreads from the most recently reviewed or scanned slide are displayed. - Automatically relocates spread on slide for scoring under high magnification - Photo of metaphase spread at high magnification for later review and documentation - Rapidly enter aberration data using software spreadsheets - Ability to permanently lock study to prevent further changes to the experimental data for all slides. - System Security limits access to unauthorized users. - Generates summary reports and statistics (chi-square, t-test) for the entire experiment Net Amount ____________________
 

Place of Performance

Address: Uniformed Services University of the Health Sciences, 4301 Jones Bridge Road, Bethesda, MD

Zip Code: 20814

Country: United States
 

Record

SN00589874-W 20040522/040520212630 (fbodaily.com)
 

Source

FedBizOpps.gov Link to This Notice
(may not be valid after Archive Date)

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