SPECIAL NOTICE
A -- Developments at NIST
- Notice Date
- 5/3/2004
- Notice Type
- Special Notice
- NAICS
- 541710
— Research and Development in the Physical, Engineering, and Life Sciences
- Contracting Office
- Department of Commerce, National Institute of Standards and Technology (NIST), Acquisition and Logistics Division, 100 Bureau Drive, Building 301, Room B129, Mail Stop 3571, Gaithersburg, MD, 20899-3571
- ZIP Code
- 20899-3571
- Solicitation Number
- Reference-Number-SN04-003
- Archive Date
- 5/31/2004
- Point of Contact
- Romena Moy, Contract Specialist, Phone (301) 975-4999, Fax (301) 975-8884,
- E-Mail Address
-
Romena.Moy@nist.gov
- Description
- DEVELOPMENTS AT NIST Researchers at the National Institute of Standards and Technology (NIST) are working on the following technologies. FOR FURTHER INFORMATION, CONTACT THE: NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY, OFFICE OF TECHNOLOGY PARTNERSHIPS, 100 BUREAU DRIVE, STOP 2200, GAITHERSBURG, MARYLAND 20899; FAX: 301-869-2751. This is not an announcement of a contract action or a grant. *** NIST DOCKET NUMBER: 04-003US Title: Controlled Vesicle Self-Assembly in Continuous Two Phase Flow Microfluidic Channels Description: The spontaneous self-assembly of phospholipids into liposomes in aqueous solution results in the encapsulation of reagents into quantized packets in a manner that mimics cellular life-processes. Traditional liposome preparation methods are conducted through mixing of bulk phases, leading to inhomogeneous chemical and/or mechanical conditions during liposome formation; hence liposomes are often polydisperse in size and lamellarity. The formation of liposomes that encapsulate reagents in a continuous 2-phase flow planar microfluidic network with precision control of size, over the range of 100 nm to 300 nm, by manipulation of liquid flow rates is shown. Creating a solvent-aqueous interfacial region in a microfluidic format that is homogenous and controllable on the length scale of a liposome demonstrates the facilitation of fine control of liposome size and polydispersity. ***
- Place of Performance
- Address: 100 Bureau Drive, Gaithersburg, MD
- Zip Code: 20899-0001
- Country: USA
- Zip Code: 20899-0001
- Record
- SN00578661-W 20040505/040503211726 (fbodaily.com)
- Source
-
FedBizOpps.gov Link to This Notice
(may not be valid after Archive Date)
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