SOURCES SOUGHT
A -- Developing a Device for Rapidly Measuring Individual Dose of Ionizing Radiation Using Human Biomarkers
- Notice Date
- 3/18/2003
- Notice Type
- Sources Sought
- Contracting Office
- Other Defense Agencies, Defense Threat Reduction Agency, Defense Threat Reduction Agency, DTRA Annex 8725 John J. Kingman Road, MSC 6201, Fort Belvoir, VA, 22060-6201
- ZIP Code
- 22060-6201
- Solicitation Number
- TDN030000567
- Archive Date
- 4/17/2003
- Point of Contact
- Cynthia Sanders, Contract Specialist, Phone (703) 325-9210, Fax (703) 325-9294,
- E-Mail Address
-
cynthia.sanders@dtra.mil
- Description
- The Defense Threat Reduction Agency (DTRA) is seeking interested sources capable of developing and providing a small, lightweight, inexpensive and minimally invasive device for rapidly measuring individual dose of ionizing radiation using human biomarkers. Ionizing radiation detection should span a broad range of doses. Different biomarkers may have to be identified to ensure detection ranging from hours to days to possibly weeks after the actual exposure. Potential sources should have demonstrated expertise in all of the following areas: Interaction of ionizing radiation with living cells Identification of responsive biomarkers, such as gene expression analysis Detection of biomarkers, using technologies such as the development of biochemical assays Quantification of biomarkers using integrated electronics and software Engineering design and prototype micro-device manufacturing capabilities In vivo validation testing This work should be completed within two years after contract award (18 months preferred). DTRA requests that potentially interested sources respond to any or all of the following: 1) Describe existing capabilities and experience with identification of biomarkers responsive to exposure to ionizing radiation and general background in radiation biology. If possible, provide reports or references to technical publications. 2) Describe existing capabilities and experience with the development of biomarker detection and quantification technologies. If possible, provide reports or references to technical publications. 3) Describe existing capabilities and experience in the design and manufacturing of highly integrated electro-mechanical-fluidic devices. If possible, provide reports or references to technical publications. 4) Describe existing capabilities and relationships for performing in vivo validation testing. Please send responses to any or all of these topics, and any other feedback, to Ms. Cynthia Sanders, Contract Specialist, via facsimile at (703) 325-9294 or e-mail (cynthia.sanders@dtra.mil) by close of business on 2 April 2003. Responses are limited to 5 pages.
- Record
- SN00282265-W 20030320/030319062243 (fbodaily.com)
- Source
-
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