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FBO DAILY ISSUE OF FEBRUARY 16, 2003 FBO #0441
SOLICITATION NOTICE

B -- A Haplotype Analysis for Cardiovascular Disease

Notice Date
2/14/2003
 
Notice Type
Solicitation Notice
 
Contracting Office
Department of Health and Human Services, National Institutes of Health, National Institute on Aging, 5600 Nathan Shock Drive, Baltimore, MD, 21224
 
ZIP Code
21224
 
Solicitation Number
LEDB02-01-03
 
Archive Date
3/31/2003
 
Point of Contact
Patricia Meise, Purchasing Agent, Phone 410-558-8043, Fax 410-558-8319,
 
E-Mail Address
meisep@grc.nia.nih.gov
 
Description
The Geriatric Epidemiology Section, LEDB, IRP, NIA, Gateway Bldg., Room 3C309, 7201 Wisconsin Avenue, Bethesda, MD 20892 intends to negotiate on a sole source basis with Wake Forest University, Gerontology Laboratory, 1 Medical Center Bldg, Winston-Salem, NC 27157. A pilot study in 400 participants of the Health ABC cohort has indicated that the frequencies of the 7 (the other 2 not available now) polymorphisms of PAI-gene in the Health ADB Cohort are similar with Dr. Deborah Nicklas's population. The present study will further genotype the rest (2,600) of the Health ABC cohort so that we can investigate the association of each PAI-1 gene polymorphism with incident cariovascular disease in all participants of the Health ABC cohort and create haplotypes to examine the efects of multiple polymorphisms. For each of 2,600 prticpants, 140ng of DNA will be shipped to Wake Forest Univeristy. The genotyping of 9 polymorphisms of PAI-1 gene will be performed through MassArray System.
 
Place of Performance
Address: 1 Medical Center Blvd, Winston-Salem, NC
Zip Code: 27157
Country: USA
 
Record
SN00259683-W 20030216/030214213316 (fbodaily.com)
 
Source
FedBizOpps.gov Link to This Notice
(may not be valid after Archive Date)

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