SOLICITATION NOTICE
A -- Studies to Evaluate the Toxicologic and Carcinogenic Potential of Selected Chemicals in Lab. Animals - 3-Picoline, Cumene Hydroperoxide, N,N-Dimethyl-P-Toluidine, Gingko Biloba Extract, and Pyrogallol
- Notice Date
- 4/9/2002
- Notice Type
- Solicitation Notice
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Institute of Environmental Health Sciences, Research Contracts Branch, DERT P.O. Box 12874, 79 T.W. Alexander Dr, Bldg 4401, RTP, NC, 27709
- ZIP Code
- 27709
- Solicitation Number
- NIH-ES-02-04
- Response Due
- 6/13/2002
- Archive Date
- 6/28/2002
- Point of Contact
- Jacqueline Osgood, Contract Specialist, Phone 919-541-7596, Fax 919-541-2712, - Melissa Gentry, Contract Specialist, Phone 919-316-4625, Fax 919-558-7044,
- E-Mail Address
-
osgood@niehs.nih.gov, gentry1@niehs.nih.gov
- Description
- The purpose of this contract is to evaluate the toxicologic and carcinogenic potential of selected chemicals to which humans are exposed in the workplace or at home. This project include 14-day, 90-day, 26-Week, and 2-year studies of 3-Picoline, Cumene Hydroperoxide, N,N-Dimethyl-P-Toluidine, Gingko Biloba Extract, and Pyrogallol. The base contract award shall consist of those work activities associated with determination of bulk chemical purity and identity, and validation of dose formulation/analysis methods, any health and safety concerns that must be addressed before study start, and other aspects specifically included in Phase 1 for Task 1 (3-Picoline), Task 2 (Cumene Hydroperoxide), Task 3 (N,N-Dimethyl-p-toluidine), Task 4 (Gingko Biloba Extract), and Task 5 (Progallol). The Government may, pending the availability of funds exercise options for: 90-day study 3-Picoline, a two-year study of 3-Picoline (dosed water) (Task 1); 14-Day Study of Cumene Hydroperoxide, 90-day study of Cumene Hydroperoxide, 26-Week Study of Cumene Hydroperoxide, and a two-year study of Cumene Hydroperoxide (deremal) (Task 2); 90-day study of N,N-Dimethyl-p-toluidine, a two-year study of N,N-Dimethyl-p-toluidine (gavage) (Task 3); 90-day study of Gingko bilobao extract, two-year study of Gingko biloba extract (gavage) (Task 4);and 14-Day Study of Pyrogallo, 90-Day Study of Pyrogallo, 26-Week Study of Pyrogallol and two-year study of Pyrogallol (dermal) (Task 5). These studies shall be conducted according to the Specifications for the Conduct of Studies to Evaluate the Toxicologic and Carcinogenic Potential of Selected Chemicals in Laboratory Animals for the National Toxicology Program (NTP) dated June 2000. Award of one cost-reimbursement completion contract on January 22, 2003, on an open competition basis is contemplated as a result of this solicitation. The estimated level of effort is 1,760 labor hours for the base contract and 148,652 labor hours for all options. The estimated period of performance is approximately 52 months. Interested organizations should request either a streamlined or full RFP package by written, telephonic ((919) 541-7596), or telefax request ((919-541-2712). If no selection is made, a streamlined version of the RFP will be provided, which will include only the Statement of Work, deliverables and reporting requirements, any special requirements, mandatory qualifications, and technical evaluation criteria. After examination of the streamlined RFP, any organization interested in responding to this RFP must request the full RFP package. A copy of the streamlined and full RFP (with Statement of Work only) will be available after the release date on the Internet at http://www.niehs.nih/gov/dert/rcb/rfp.htm. Those individuals who wish to access the on-line version should follow the instructions provided in the on-line solicitation package. All responsible sources may submit a proposal which shall be considered by the Agency. Expected release date of the RFP is April 24, 2002 with proposals due June 13, 2002!!!!!
- Record
- SN00055535-W 20020411/020410063452 (fbodaily.com)
- Source
-
FedBizOpps.gov Link to This Notice
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