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FBO DAILY ISSUE OF MARCH 15, 2002 FBO #0103
SOLICITATION NOTICE

66 -- X-Ray Machine

Notice Date

3/13/2002
 

Notice Type

Solicitation Notice
 

Contracting Office

Department of Health and Human Services, National Institutes of Health, National Cancer Institute, Research Contracts Br., 6120 Executive Blvd. EPS Room 604, Rockville, MD, 20852
 

ZIP Code

20852
 

Solicitation Number

RFQ-NCI-20027-NG
 

Response Due

3/28/2002
 

Archive Date

4/12/2002
 

Point of Contact

Malinda Holdcraft, Purchasing Agent, Phone (301) 402-4509, Fax (301) 402-4513, - Caren Rasmussen, Lead Contract Specialist, Phone (301) 402-4509, Fax (301) 402-4513,
 

E-Mail Address

mh139x@nih.gov, rasmusc@mail.nih.gov
 

Description

The National Cancer Institute (NCI), Laboratory of Molecular Cell Biology (LMCB), plans to procure a Faxiton X-Ray machine with Faxitron X-Ray Corp., 1670 Barclay Blvd., Buffalo Grove, Illinois, 60089. The LMCB investigates basic cellular processes of homeostasis, growth, division and differentiation, with an emphasis on the molecular biology of chromosomes and the cell nucleus. Research at the eukaryotic genome maintenance unit is aimed at understanding how living organisms safeguard their genomes against DNA damaging agents, such as irradiation. The fruit-fly Drosophila is used as a model organism for these studies. This particular X-ray machine will allow the laboratory to X-ray irradiate fruit flies at different developmental stages to induce cellular damages and to generate mutations. The X-ray machine will generate DNA damages and facilitate a better understanding of how Drosophila cells detect and repair these damages. The machine will also be used to induce mutations that cause defects in DNA damage repair. These mutational studies help the laboratory to elucidate specific functions of genes involved in damage repair. The required instrument shall have a shelfed chamber on which specimen would be placed. The individual researcher must have control over the dosage of irradiation from 100 to 10,000 rads. The machine must be able to deliver 10,000 rads for a period shorter than ten (10) minutes so that the specimen will not be dried during irradiation. In addition, the instrument must be compact so that it can be placed in an easily accessible place. The following minimum features are required for the Faxitron X-ray machine: 1) >1000 Rad/min so that a dosage of 10,000 Rad can be delivered at less than ten (10) minutes. This is critical for the experiments in two ways; (a) fruit flies will not be killed due to desiccation in the irrational chamber and, (b) fruit flies will still be at sleep which facilitates post-irradiation manipulation; 2) machine must be "self-cooling" so that no external source of coolant is needed; 3) radiation dosage can be very finely adjusted by changing the timer at one-second increments; 4) motor driven turntable which provides a means of improving uniformity of the absorbed radiation dose and; 5) machine is relatively small, allows easy placement in the laboratory and easy transportation. Faxitron X-ray Corp is the only source known to the NCI Researcher that can provide the aforementioned X-ray machine. This notice is not a request for competitive quotation. However, if any interested party believes it can meet the above requirements, it may submit a statement of capabilities. The capability statement and any other furnished information must be in writing and must contain material in sufficient detail to allow NCI to determine if the party can fully meet the requirements. Capability statements must be received in the contracting office by 1:00 PM EST, (local Washington, D.C. time), on March 28, 2002. If you have any questions, please contact Malinda Holdcraft, Purchasing Agent on (301) 402-4509. A determination by the Government not to compete this proposed requirement based on responses to this notice is solely within the discretion of the Government. Information received shall be considered solely for the purpose of determining whether to conduct a competitive procurement. No collect calls will be accepted. Faxed capability statements will not be accepted. If submitting capability statements, provide one original and three copies.
 

Place of Performance

Address: NIH/NCI, 9000 Rockville Pike, Bethesda, Maryland

Zip Code: 20892

Country: USA
 

Record

SN00042014-W 20020315/020313213136 (fbodaily.com)
 

Source

FedBizOpps.gov Link to This Notice
(may not be valid after Archive Date)

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