SOLICITATION NOTICE
A -- Preclinical Toxicology Studies of Chemopreventive Agents
- Notice Date
- 3/13/2002
- Notice Type
- Solicitation Notice
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Cancer Institute, Research Contracts Br., 6120 Executive Blvd. EPS Room 604, Rockville, MD, 20852
- ZIP Code
- 20852
- Solicitation Number
- N01-CN-25012-02
- Response Due
- 6/4/2002
- Archive Date
- 6/19/2002
- Point of Contact
- James Chestnut, Contract Specialist, Phone (301) 496-8604, Fax (301) 402-8579, - Gary Topper, Contracting Officer, Phone (301) 435-3793, Fax (301) 402-8579,
- E-Mail Address
-
jc572n@nih.gov, gt22b@nih.gov
- Description
- The Chemoprevention Branch, Division of Cancer Prevention of the National Cancer Institute (NCI), through the Preclinical Toxicology of Chemopreventive Agents Master Agreement (MA) pool is seeking to issue Master Agreement Orders for the following Workstatements (1) 28-day oral toxicity of farnesol in rats (treatment/recovery) (2) Chronic oral toxicity studies of characterized isoflavone mixture in rats and dogs (3) Genotoxicity: Lymphoma assay for curcumin C3 complex (4) 14/28 Day oral toxicity with farnesol in dogs (5) Dermal sensitization (Buehler test) for Nia-114 (6) Dermal irritation on multiple treatment- Nia-114 (7) Metabolism of radioactive fluasterone in dogs (8) Bioanalytical method development and drug metabolism [2 awards] (9) Drug exposure on different dosing paradigm (10) Drug metabolism/drug interactions in vitro studies [2 awards] (11) Absorption, distribution, metabolism and excretion of 14C-Nia-114 (12) Analytical method development and validation for Nia-114 and metabolites The Master Agreement holder(s) shall undertake, under direction of the Government, those protocols as addressed in each Workstatement. This RFP will sent by mail to the members of the Pool. Those interested in all or part of this solicitation should forward their request via email to James N. Chestnut at jc572n@nih.gov. MANDATORY QUALIFICATION CRITERION: NCI WILL ONLY ACCEPT PROPOSALS FROM CURRENT MASTER AGREEMENT HOLDERS IN THE PRECLINICAL TOXICOLOGY OF CHEMOPREVENTIVE AGENTS MASTER AGREEMENT POOL. Current MA Pool members are as follows: 1. MPI Research, LLC 2. Springborn Laboratories, Inc. 3. Southern Research Institute 4. IIT Research Institute 5. SRI International 6. University of Illinois at Chicago 7. Research Triangle Institute 8. Litron Laboratories 9. Lovelace Biomedical and Environmental Research Institute The code for this project based on the North American Industry Classification System (NAICS) is 541710. Those who are not currently listed and wish to considered for inclusion in a pool should consult the Research Contracts Branchs website at http://amb.nci.nih.gov. Click the Current Requests for Proposals link. It is anticipated that this RFP will be available by 04/14/2002. See Note 26. Questions should be directed, via facsimile or email, to James N. Chestnut, Contract Specialist, Research Contracts Branch, Prevention, Control and Population Science Section, Research Contracts Branch, National Cancer Institute, Executive Plaza South, Room 635, MSC7226, Bethesda, MD 20892-7226. Phone: (301)496-8604; FAX: (301)402-8579; email: jc572n@nih.gov.
- Record
- SN00041034-W 20020314/020313095120 (fbodaily.com)
- Source
-
FedBizOpps.gov Link to This Notice
(may not be valid after Archive Date)
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